You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Interaction between the 5-HT system and the basal ganglia: functional implication and therapeutic perspective in Parkinson's disease
|
|---|---|
| Published in |
Frontiers in Neural Circuits, March 2014
|
| DOI | 10.3389/fncir.2014.00021 |
| Pubmed ID | |
| Authors |
Cristina Miguelez, Teresa Morera-Herreras, Maria Torrecilla, Jose A. Ruiz-Ortega, Luisa Ugedo |
| Abstract |
The neurotransmitter serotonin (5-HT) has a multifaceted function in the modulation of information processing through the activation of multiple receptor families, including G-protein-coupled receptor subtypes (5-HT1, 5-HT2, 5-HT4-7) and ligand-gated ion channels (5-HT3). The largest population of serotonergic neurons is located in the midbrain, specifically in the raphe nuclei. Although the medial and dorsal raphe nucleus (DRN) share common projecting areas, in the basal ganglia (BG) nuclei serotonergic innervations come mainly from the DRN. The BG are a highly organized network of subcortical nuclei composed of the striatum (caudate and putamen), subthalamic nucleus (STN), internal and external globus pallidus (or entopeduncular nucleus in rodents, GPi/EP and GPe) and substantia nigra (pars compacta, SNc, and pars reticulata, SNr). The BG are part of the cortico-BG-thalamic circuits, which play a role in many functions like motor control, emotion, and cognition and are critically involved in diseases such as Parkinson's disease (PD). This review provides an overview of serotonergic modulation of the BG at the functional level and a discussion of how this interaction may be relevant to treating PD and the motor complications induced by chronic treatment with L-DOPA. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 140 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| Chile | 1 | <1% |
| France | 1 | <1% |
| Canada | 1 | <1% |
| China | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 134 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 27 | 19% |
| Researcher | 25 | 18% |
| Student > Bachelor | 17 | 12% |
| Student > Master | 15 | 11% |
| Student > Doctoral Student | 10 | 7% |
| Other | 25 | 18% |
| Unknown | 21 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 42 | 30% |
| Agricultural and Biological Sciences | 30 | 21% |
| Medicine and Dentistry | 20 | 14% |
| Psychology | 11 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 2% |
| Other | 10 | 7% |
| Unknown | 24 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 July 2016.
All research outputs
#22,983,009
of 25,626,416 outputs
Outputs from Frontiers in Neural Circuits
#1,105
of 1,301 outputs
Outputs of similar age
#218,641
of 250,203 outputs
Outputs of similar age from Frontiers in Neural Circuits
#18
of 18 outputs
Altmetric has tracked 25,626,416 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,301 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,203 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.