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A new era for functional labeling of neurons: activity-dependent promoters have come of age

Overview of attention for article published in Frontiers in Neural Circuits, April 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

blogs
2 blogs
twitter
4 X users
facebook
1 Facebook page
googleplus
1 Google+ user

Citations

dimensions_citation
134 Dimensions

Readers on

mendeley
589 Mendeley
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Title
A new era for functional labeling of neurons: activity-dependent promoters have come of age
Published in
Frontiers in Neural Circuits, April 2014
DOI 10.3389/fncir.2014.00037
Pubmed ID
Authors

Takashi Kawashima, Hiroyuki Okuno, Haruhiko Bito

Abstract

Genetic labeling of neurons with a specific response feature is an emerging technology for precise dissection of brain circuits that are functionally heterogeneous at the single-cell level. While immediate early gene mapping has been widely used for decades to identify brain regions which are activated by external stimuli, recent characterization of the promoter and enhancer elements responsible for neuronal activity-dependent transcription have opened new avenues for live imaging of active neurons. Indeed, these advancements provided the basis for a growing repertoire of novel experiments to address the role of active neuronal networks in cognitive behaviors. In this review, we summarize the current literature on the usage and development of activity-dependent promoters and discuss the future directions of this expanding new field.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 589 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 8 1%
Japan 5 <1%
Germany 4 <1%
France 3 <1%
Mexico 1 <1%
Switzerland 1 <1%
United Kingdom 1 <1%
China 1 <1%
Unknown 565 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 161 27%
Researcher 126 21%
Student > Bachelor 59 10%
Student > Master 57 10%
Professor 25 4%
Other 92 16%
Unknown 69 12%
Readers by discipline Count As %
Neuroscience 210 36%
Agricultural and Biological Sciences 176 30%
Biochemistry, Genetics and Molecular Biology 39 7%
Medicine and Dentistry 35 6%
Engineering 11 2%
Other 37 6%
Unknown 81 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 June 2021.
All research outputs
#2,210,888
of 25,806,080 outputs
Outputs from Frontiers in Neural Circuits
#84
of 1,303 outputs
Outputs of similar age
#21,462
of 242,699 outputs
Outputs of similar age from Frontiers in Neural Circuits
#1
of 22 outputs
Altmetric has tracked 25,806,080 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,303 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,699 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.