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Somatostatin and Somatostatin-Containing Neurons in Shaping Neuronal Activity and Plasticity

Overview of attention for article published in Frontiers in Neural Circuits, June 2016
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  • Good Attention Score compared to outputs of the same age (65th percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

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Title
Somatostatin and Somatostatin-Containing Neurons in Shaping Neuronal Activity and Plasticity
Published in
Frontiers in Neural Circuits, June 2016
DOI 10.3389/fncir.2016.00048
Pubmed ID
Authors

Monika Liguz-Lecznar, Joanna Urban-Ciecko, Malgorzata Kossut

Abstract

Since its discovery over four decades ago, somatostatin (SOM) receives growing scientific and clinical interest. Being localized in the nervous system in a subset of interneurons somatostatin acts as a neurotransmitter or neuromodulator and its role in the fine-tuning of neuronal activity and involvement in synaptic plasticity and memory formation are widely recognized in the recent literature. Combining transgenic animals with electrophysiological, anatomical and molecular methods allowed to characterize several subpopulations of somatostatin-containing interneurons possessing specific anatomical and physiological features engaged in controlling the output of cortical excitatory neurons. Special characteristic and connectivity of somatostatin-containing neurons set them up as significant players in shaping activity and plasticity of the nervous system. However, somatostatin is not just a marker of particular interneuronal subpopulation. Somatostatin itself acts pre- and postsynaptically, modulating excitability and neuronal responses. In the present review, we combine the knowledge regarding somatostatin and somatostatin-containing interneurons, trying to incorporate it into the current view concerning the role of the somatostatinergic system in cortical plasticity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 254 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Israel 1 <1%
Finland 1 <1%
United Kingdom 1 <1%
Spain 1 <1%
United States 1 <1%
Unknown 249 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 60 24%
Student > Master 37 15%
Researcher 30 12%
Student > Bachelor 28 11%
Student > Doctoral Student 18 7%
Other 34 13%
Unknown 47 19%
Readers by discipline Count As %
Neuroscience 105 41%
Agricultural and Biological Sciences 39 15%
Biochemistry, Genetics and Molecular Biology 18 7%
Medicine and Dentistry 11 4%
Psychology 6 2%
Other 18 7%
Unknown 57 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2016.
All research outputs
#7,756,047
of 24,877,044 outputs
Outputs from Frontiers in Neural Circuits
#446
of 1,286 outputs
Outputs of similar age
#119,010
of 359,336 outputs
Outputs of similar age from Frontiers in Neural Circuits
#5
of 22 outputs
Altmetric has tracked 24,877,044 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 1,286 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 359,336 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.