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Mendeley readers
Attention Score in Context
| Title |
Is lactate a volume transmitter of metabolic states of the brain?
|
|---|---|
| Published in |
Frontiers in Neuroenergetics, January 2012
|
| DOI | 10.3389/fnene.2012.00005 |
| Pubmed ID | |
| Authors |
Linda H. Bergersen, Albert Gjedde |
| Abstract |
We present the perspective that lactate is a volume transmitter of cellular signals in brain that acutely and chronically regulate the energy metabolism of large neuronal ensembles. From this perspective, we interpret recent evidence to mean that lactate transmission serves the maintenance of network metabolism by two different mechanisms, one by regulating the formation of cAMP via the lactate receptor GPR81, the other by adjusting the NADH/NAD(+) redox ratios, both linked to the maintenance of brain energy turnover and possibly cerebral blood flow. The role of lactate as mediator of metabolic information rather than metabolic substrate answers a number of questions raised by the controversial oxidativeness of astrocytic metabolism and its contribution to neuronal function. |
Mendeley readers
The data shown below were compiled from readership statistics for 126 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Canada | 1 | <1% |
| Chile | 1 | <1% |
| Spain | 1 | <1% |
| Luxembourg | 1 | <1% |
| Unknown | 120 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 22% |
| Researcher | 25 | 20% |
| Student > Master | 16 | 13% |
| Professor | 10 | 8% |
| Student > Bachelor | 10 | 8% |
| Other | 25 | 20% |
| Unknown | 12 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 32 | 25% |
| Neuroscience | 25 | 20% |
| Medicine and Dentistry | 16 | 13% |
| Biochemistry, Genetics and Molecular Biology | 14 | 11% |
| Sports and Recreations | 4 | 3% |
| Other | 15 | 12% |
| Unknown | 20 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 June 2014.
All research outputs
#20,231,392
of 22,757,090 outputs
Outputs from Frontiers in Neuroenergetics
#37
of 39 outputs
Outputs of similar age
#221,369
of 244,286 outputs
Outputs of similar age from Frontiers in Neuroenergetics
#6
of 7 outputs
Altmetric has tracked 22,757,090 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 39 research outputs from this source. They receive a mean Attention Score of 4.6. This one scored the same or higher as 2 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,286 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one.