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Cognitive Functions in Ataxia with Oculomotor Apraxia Type 2

Overview of attention for article published in Frontiers in Neurology, January 2012
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  • Above-average Attention Score compared to outputs of the same age and source (64th percentile)

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1 X user
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1 Wikipedia page

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9 Dimensions

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Title
Cognitive Functions in Ataxia with Oculomotor Apraxia Type 2
Published in
Frontiers in Neurology, January 2012
DOI 10.3389/fneur.2012.00125
Pubmed ID
Authors

Peter Klivényi, Dezso Nemeth, Tamas Sefcsik, Karolina Janacsek, Ildiko Hoffmann, Gabor Peter Haden, Zsuzsa Londe, Laszlo Vecsei

Abstract

Background: Ataxia with oculomotor apraxia type 2 (AOA2) is characterized by cerebellar atrophy, peripheral neuropathy, oculomotor apraxia, and elevated serum alpha-fetoprotein (AFP) levels. The disease is caused by a recessive mutation in the senataxin gene. Since it is a very rare cerebellar disorder, no detailed examination of cognitive functions in AOA2 has been published to date. The aim of the present study was to investigate the neuropsychological profile of a 54-year-old patient with AOA2. Methods: A broad range of neuropsychological examination protocol was administered including the following domains: short-term, working- and episodic-memories, executive functions, implicit sequence learning, and the temporal parameters of speech. Results: The performance on the Listening Span, Letter Fluency, Serial Reaction Time Task, and pause ratio in speech was 2 or more standard deviations (SD) lower compared to controls, and 1 SD lower on Backward Digit Span, Semantic Fluency, articulation rate, and speech tempo. Conclusion: These findings indicate that the pathogenesis of the cerebrocerebellar circuit in AOA2 is responsible for the weaker coordination of complex cognitive functions such as working memory, executive functions, speech, and sequence learning.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 18%
Student > Bachelor 3 14%
Professor 3 14%
Student > Ph. D. Student 3 14%
Student > Doctoral Student 2 9%
Other 5 23%
Unknown 2 9%
Readers by discipline Count As %
Psychology 5 23%
Medicine and Dentistry 4 18%
Neuroscience 3 14%
Nursing and Health Professions 2 9%
Arts and Humanities 2 9%
Other 1 5%
Unknown 5 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 January 2023.
All research outputs
#7,371,766
of 23,230,825 outputs
Outputs from Frontiers in Neurology
#4,585
of 12,149 outputs
Outputs of similar age
#68,683
of 246,127 outputs
Outputs of similar age from Frontiers in Neurology
#39
of 117 outputs
Altmetric has tracked 23,230,825 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 12,149 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 246,127 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 117 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.