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The Involvement of Cholinergic Neurons in the Spreading of Tau Pathology

Overview of attention for article published in Frontiers in Neurology, January 2013
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Title
The Involvement of Cholinergic Neurons in the Spreading of Tau Pathology
Published in
Frontiers in Neurology, January 2013
DOI 10.3389/fneur.2013.00074
Pubmed ID
Authors

Diana Simón, Félix Hernández, Jesús Avila

Abstract

Long time ago, it was described the selective loss of cholinergic neurons during the development of Alzheimer disease (AD). Recently, it has been suggested that tau protein may play a role in that loss of cholinergic neurons through a mechanism involving the interaction of extracellular tau with M1/M3 muscarinic receptors present in the cholinergic neurons. This interaction between tau and muscarinic receptors may be a way, although not the only one, to explain the spreading of tau pathology occurring in AD.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Unknown 54 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 31%
Researcher 10 18%
Student > Master 8 15%
Other 5 9%
Student > Bachelor 4 7%
Other 4 7%
Unknown 7 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 25%
Neuroscience 12 22%
Medicine and Dentistry 8 15%
Biochemistry, Genetics and Molecular Biology 3 5%
Immunology and Microbiology 2 4%
Other 7 13%
Unknown 9 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 June 2013.
All research outputs
#20,195,024
of 22,712,476 outputs
Outputs from Frontiers in Neurology
#8,627
of 11,620 outputs
Outputs of similar age
#248,758
of 280,743 outputs
Outputs of similar age from Frontiers in Neurology
#117
of 210 outputs
Altmetric has tracked 22,712,476 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,620 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,743 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 210 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.