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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Mechanisms of Levetiracetam in the Control of Status Epilepticus and Epilepsy
|
|---|---|
| Published in |
Frontiers in Neurology, January 2014
|
| DOI | 10.3389/fneur.2014.00011 |
| Pubmed ID | |
| Authors |
Laxmikant S. Deshpande, Robert J. DeLorenzo |
| Abstract |
Status epilepticus (SE) is a major clinical emergency that is associated with high mortality and morbidity. SE causes significant neuronal injury and survivors are at a greater risk of developing acquired epilepsy and other neurological morbidities, including depression and cognitive deficits. Benzodiazepines and some anticonvulsant agents are drugs of choice for initial SE management. Despite their effectiveness, over 40% of SE cases are refractory to the initial treatment with two or more medications. Thus, there is an unmet need of developing newer anti-SE drugs. Levetiracetam (LEV) is a widely prescribed anti-epileptic drug that has been reported to be used in SE cases, especially in benzodiazepine-resistant SE or where phenytoin cannot be used due to allergic side-effects. Levetiracetam's non-classical anti-epileptic mechanisms of action, favorable pharmacokinetic profile, general lack of central depressant effects, and lower incidence of drug interactions contribute to its use in SE management. This review will focus on LEV's unique mechanism of action that makes it a viable candidate for SE treatment. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 33% |
| Venezuela, Bolivarian Republic of | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 200 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Italy | 1 | <1% |
| Unknown | 198 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 34 | 17% |
| Researcher | 21 | 11% |
| Student > Ph. D. Student | 19 | 10% |
| Student > Doctoral Student | 17 | 9% |
| Other | 15 | 8% |
| Other | 47 | 24% |
| Unknown | 47 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 54 | 27% |
| Neuroscience | 25 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 23 | 12% |
| Agricultural and Biological Sciences | 15 | 8% |
| Biochemistry, Genetics and Molecular Biology | 9 | 5% |
| Other | 22 | 11% |
| Unknown | 52 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 December 2020.
All research outputs
#6,085,663
of 22,741,406 outputs
Outputs from Frontiers in Neurology
#4,048
of 11,651 outputs
Outputs of similar age
#71,779
of 305,211 outputs
Outputs of similar age from Frontiers in Neurology
#6
of 27 outputs
Altmetric has tracked 22,741,406 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 11,651 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,211 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.