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Fish Oil Diet Associated with Acute Reperfusion Related Hemorrhage, and with Reduced Stroke-Related Sickness Behaviors and Motor Impairment

Overview of attention for article published in Frontiers in Neurology, January 2014
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Title
Fish Oil Diet Associated with Acute Reperfusion Related Hemorrhage, and with Reduced Stroke-Related Sickness Behaviors and Motor Impairment
Published in
Frontiers in Neurology, January 2014
DOI 10.3389/fneur.2014.00014
Pubmed ID
Authors

Michaela C. Pascoe, David W. Howells, David P. Crewther, Nicki Constantinou, Leeanne M. Carey, Sarah S. Rewell, Giovanni M. Turchini, Gunveen Kaur, Sheila G. Crewther

Abstract

Ischemic stroke is associated with motor impairment and increased incidence of affective disorders such as anxiety/clinical depression. In non-stroke populations, successful management of such disorders and symptoms has been reported following diet supplementation with long chain omega-3-polyunsaturated-fatty-acids (PUFAs). However, the potential protective effects of PUFA supplementation on affective behaviors after experimentally induced stroke and sham surgery have not been examined previously. This study investigated the behavioral effects of PUFA supplementation over a 6-week period following either middle cerebral artery occlusion or sham surgery in the hooded-Wistar rat. The PUFA diet supplied during the acclimation period prior to surgery was found to be associated with an increased risk of acute hemorrhage following the reperfusion component of the surgery. In surviving animals, PUFA supplementation did not influence infarct size as determined 6 weeks after surgery, but did decrease omega-6-fatty-acid levels, moderate sickness behaviors, acute motor impairment, and longer-term locomotor hyperactivity and depression/anxiety-like behavior.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Romania 1 3%
Unknown 34 94%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 19%
Researcher 6 17%
Student > Ph. D. Student 5 14%
Professor 3 8%
Student > Postgraduate 2 6%
Other 5 14%
Unknown 8 22%
Readers by discipline Count As %
Medicine and Dentistry 9 25%
Neuroscience 7 19%
Agricultural and Biological Sciences 4 11%
Psychology 2 6%
Social Sciences 1 3%
Other 3 8%
Unknown 10 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2014.
All research outputs
#20,219,902
of 22,743,667 outputs
Outputs from Frontiers in Neurology
#8,653
of 11,657 outputs
Outputs of similar age
#264,758
of 305,223 outputs
Outputs of similar age from Frontiers in Neurology
#21
of 27 outputs
Altmetric has tracked 22,743,667 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,657 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,223 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.