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Blast TBI Models, Neuropathology, and Implications for Seizure Risk

Overview of attention for article published in Frontiers in Neurology, April 2014
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Title
Blast TBI Models, Neuropathology, and Implications for Seizure Risk
Published in
Frontiers in Neurology, April 2014
DOI 10.3389/fneur.2014.00047
Pubmed ID
Authors

S. Krisztian Kovacs, Fabio Leonessa, Geoffrey S. F. Ling

Abstract

Traumatic brain injury (TBI) due to explosive blast exposure is a leading combat casualty. It is also implicated as a key contributor to war related mental health diseases. A clinically important consequence of all types of TBI is a high risk for development of seizures and epilepsy. Seizures have been reported in patients who have suffered blast injuries in the Global War on Terror but the exact prevalence is unknown. The occurrence of seizures supports the contention that explosive blast leads to both cellular and structural brain pathology. Unfortunately, the exact mechanism by which explosions cause brain injury is unclear, which complicates development of meaningful therapies and mitigation strategies. To help improve understanding, detailed neuropathological analysis is needed. For this, histopathological techniques are extremely valuable and indispensable. In the following we will review the pathological results, including those from immunohistochemical and special staining approaches, from recent preclinical explosive blast studies.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Denmark 1 1%
Unknown 72 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 19%
Researcher 10 14%
Student > Bachelor 8 11%
Student > Doctoral Student 6 8%
Professor > Associate Professor 5 7%
Other 11 15%
Unknown 20 27%
Readers by discipline Count As %
Medicine and Dentistry 15 20%
Neuroscience 11 15%
Agricultural and Biological Sciences 11 15%
Engineering 4 5%
Biochemistry, Genetics and Molecular Biology 3 4%
Other 10 14%
Unknown 20 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2014.
All research outputs
#20,228,193
of 22,753,345 outputs
Outputs from Frontiers in Neurology
#8,667
of 11,665 outputs
Outputs of similar age
#194,900
of 228,038 outputs
Outputs of similar age from Frontiers in Neurology
#33
of 54 outputs
Altmetric has tracked 22,753,345 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,665 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.