Title |
Recent Advances and Future Challenges in the Genetics of Multiple Sclerosis
|
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Published in |
Frontiers in Neurology, July 2014
|
DOI | 10.3389/fneur.2014.00130 |
Pubmed ID | |
Authors |
Christina M. Lill |
Abstract |
Multiple sclerosis (MS) is the most common auto-inflammatory disease of the central nervous system, affecting more than 2 million individuals worldwide. It is a genetically complex disease, in which a substantial part of a person's liability to develop MS is caused by a combination of multiple genetic and non-genetic (e.g., environmental) risk factors. Increasing this complexity, many of the involved risk factors likely interact in an intricate and hitherto ill-defined fashion. Despite these complexities, and owing greatly to the advent and application of large-scale genome-wide association studies, our understanding of the genetic factors underlying MS etiology has begun to gain unprecedented momentum. In this perspective, I will summarize some recent advances and outline future challenges in MS genetics research. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Brazil | 2 | 2% |
Portugal | 1 | 1% |
Germany | 1 | 1% |
United Kingdom | 1 | 1% |
Mexico | 1 | 1% |
United States | 1 | 1% |
Unknown | 86 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 17 | 18% |
Researcher | 14 | 15% |
Student > Master | 14 | 15% |
Student > Bachelor | 11 | 12% |
Student > Doctoral Student | 8 | 9% |
Other | 16 | 17% |
Unknown | 13 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 25 | 27% |
Agricultural and Biological Sciences | 21 | 23% |
Biochemistry, Genetics and Molecular Biology | 12 | 13% |
Neuroscience | 6 | 6% |
Psychology | 5 | 5% |
Other | 9 | 10% |
Unknown | 15 | 16% |