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Biochemical Markers of Physical Exercise on Mild Cognitive Impairment and Dementia: Systematic Review and Perspectives

Overview of attention for article published in Frontiers in Neurology, August 2015
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

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1 news outlet
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8 X users

Citations

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55 Dimensions

Readers on

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177 Mendeley
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Title
Biochemical Markers of Physical Exercise on Mild Cognitive Impairment and Dementia: Systematic Review and Perspectives
Published in
Frontiers in Neurology, August 2015
DOI 10.3389/fneur.2015.00187
Pubmed ID
Authors

Camilla Steen Jensen, Steen Gregers Hasselbalch, Gunhild Waldemar, Anja Hviid Simonsen

Abstract

The cognitive effects of physical exercise in patients with dementia disorders or mild cognitive impairment have been examined in various studies; however the biochemical effects of exercise from intervention studies are largely unknown. The objective of this systematic review is to investigate the published results on biomarkers in physical exercise intervention studies in patients with MCI or dementia. The PubMed database was searched for studies from 1976 to February 2015. We included intervention studies investigating the effect of physical exercise activity on biomarkers in patients with MCI or dementia. A total of eight studies were identified (n = 447 patients) evaluating exercise regimes with variable duration (single session-three sessions/week for 26 weeks) and intensity (light-resistance training-high-intensity aerobic exercise). Various biomarkers were measured before and after intervention. Seven of the eight studies found a significant effect on their selected biomarkers with a positive effect of exercise on brain-derived neurotrophic factor, cholesterol, testosterone, estradiol, dehydroepiadrosterone, and insulin in the intervention groups compared with controls. Although few studies suggest a beneficial effect on selected biomarkers, we need more knowledge of the biochemical effect of physical exercise in dementia or MCI.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 177 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 2 1%
Portugal 1 <1%
Unknown 174 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 28 16%
Student > Ph. D. Student 26 15%
Student > Bachelor 21 12%
Student > Doctoral Student 16 9%
Student > Postgraduate 12 7%
Other 35 20%
Unknown 39 22%
Readers by discipline Count As %
Medicine and Dentistry 27 15%
Sports and Recreations 22 12%
Psychology 20 11%
Neuroscience 14 8%
Nursing and Health Professions 14 8%
Other 31 18%
Unknown 49 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 August 2022.
All research outputs
#2,292,941
of 23,009,818 outputs
Outputs from Frontiers in Neurology
#1,161
of 11,904 outputs
Outputs of similar age
#32,128
of 268,028 outputs
Outputs of similar age from Frontiers in Neurology
#11
of 54 outputs
Altmetric has tracked 23,009,818 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,904 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,028 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.