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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Role of the Contralesional Hemisphere in Post-Stroke Recovery of Upper Extremity Motor Function
|
|---|---|
| Published in |
Frontiers in Neurology, October 2015
|
| DOI | 10.3389/fneur.2015.00214 |
| Pubmed ID | |
| Authors |
Cathrin M. Buetefisch |
| Abstract |
Identification of optimal treatment strategies to improve recovery is limited by the incomplete understanding of the neurobiological principles of recovery. Motor cortex (M1) reorganization of the lesioned hemisphere (ipsilesional M1) plays a major role in post-stroke motor recovery and is a primary target for rehabilitation therapy. Reorganization of M1 in the hemisphere contralateral to the stroke (contralesional M1) may, however, serve as an additional source of cortical reorganization and related recovery. The extent and outcome of such reorganization depends on many factors, including lesion size and time since stroke. In the chronic phase post-stroke, contralesional M1 seems to interfere with motor function of the paretic limb in a subset of patients, possibly through abnormally increased inhibition of lesioned M1 by the contralesional M1. In such patients, decreasing contralesional M1 excitability by cortical stimulation results in improved performance of the paretic limb. However, emerging evidence suggests a potentially supportive role of contralesional M1. After infarction of M1 or its corticospinal projections, there is abnormally increased excitatory neural activity and activation in contralesional M1 that correlates with favorable motor recovery. Decreasing contralesional M1 excitability in these patients may result in deterioration of paretic limb performance. In animal stroke models, reorganizational changes in contralesional M1 depend on the lesion size and rehabilitation treatment and include long-term changes in neurotransmitter systems, dendritic growth, and synapse formation. While there is, therefore, some evidence that activity in contralesional M1 will impact the extent of motor function of the paretic limb in the subacute and chronic phase post-stroke and may serve as a new target for rehabilitation treatment strategies, the precise factors that specifically influence its role in the recovery process remain to be defined. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | 33% |
| Switzerland | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 241 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Germany | 1 | <1% |
| Chile | 1 | <1% |
| Hong Kong | 1 | <1% |
| India | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 235 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 44 | 18% |
| Researcher | 40 | 17% |
| Student > Master | 32 | 13% |
| Student > Bachelor | 31 | 13% |
| Student > Doctoral Student | 13 | 5% |
| Other | 32 | 13% |
| Unknown | 49 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 53 | 22% |
| Medicine and Dentistry | 39 | 16% |
| Nursing and Health Professions | 21 | 9% |
| Agricultural and Biological Sciences | 16 | 7% |
| Engineering | 14 | 6% |
| Other | 28 | 12% |
| Unknown | 70 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 November 2015.
All research outputs
#14,718,998
of 23,577,654 outputs
Outputs from Frontiers in Neurology
#6,002
of 12,531 outputs
Outputs of similar age
#147,188
of 281,366 outputs
Outputs of similar age from Frontiers in Neurology
#38
of 61 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,531 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 281,366 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 61 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.