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Clinical Subgroups in Bilateral Meniere Disease

Overview of attention for article published in Frontiers in Neurology, October 2016
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

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15 X users
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5 Facebook pages

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121 Mendeley
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Title
Clinical Subgroups in Bilateral Meniere Disease
Published in
Frontiers in Neurology, October 2016
DOI 10.3389/fneur.2016.00182
Pubmed ID
Authors

Lidia Frejo, Andres Soto-Varela, Sofía Santos-Perez, Ismael Aran, Angel Batuecas-Caletrio, Vanesa Perez-Guillen, Herminio Perez-Garrigues, Jesus Fraile, Eduardo Martin-Sanz, Maria C. Tapia, Gabriel Trinidad, Ana María García-Arumi, Rocío González-Aguado, Juan M. Espinosa-Sanchez, Pedro Marques, Paz Perez, Jesus Benitez, Jose A. Lopez-Escamez

Abstract

Meniere disease (MD) is a heterogeneous clinical condition characterized by sensorineural hearing loss, episodic vestibular symptoms, and tinnitus associated with several comorbidities, such as migraine or autoimmune disorders (AD). The frequency of bilateral involvement may range from 5 to 50%, and it depends on the duration of the disease. We have performed a two-step cluster analysis in 398 patients with bilateral MD (BMD) to identify the best predictors to define clinical subgroups with a potential different etiology to improve the phenotyping of BMD and to develop new treatments. We have defined five clinical variants in BMD. Group 1 is the most frequently found, includes 46% of patients, and is defined by metachronic hearing loss without migraine and without AD. Group 2 is found in 17% of patients, and it is defined by synchronic hearing loss without migraine or AD. Group 3, with 13% of patients, is characterized by familial MD, while group 4, that includes 12% of patients, is associated by the presence of migraine in all cases. Group 5 is found in 11% of patients and is defined by AD. This approach can be helpful in selecting patients for genetic and clinical research. However, further studies will be required to improve the phenotyping in these clinical variants for a better understanding of the diverse etiological factors contributing to BMD.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 121 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 121 100%

Demographic breakdown

Readers by professional status Count As %
Other 16 13%
Researcher 15 12%
Student > Master 12 10%
Professor > Associate Professor 9 7%
Student > Bachelor 8 7%
Other 27 22%
Unknown 34 28%
Readers by discipline Count As %
Medicine and Dentistry 51 42%
Unspecified 4 3%
Biochemistry, Genetics and Molecular Biology 4 3%
Agricultural and Biological Sciences 4 3%
Immunology and Microbiology 4 3%
Other 13 11%
Unknown 41 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2021.
All research outputs
#2,537,852
of 22,715,151 outputs
Outputs from Frontiers in Neurology
#1,347
of 11,620 outputs
Outputs of similar age
#45,741
of 313,465 outputs
Outputs of similar age from Frontiers in Neurology
#8
of 80 outputs
Altmetric has tracked 22,715,151 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,620 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,465 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.