Title |
Zika Virus Infection and Guillain–Barré Syndrome in Three Patients from Suriname
|
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Published in |
Frontiers in Neurology, December 2016
|
DOI | 10.3389/fneur.2016.00233 |
Pubmed ID | |
Authors |
Thomas Langerak, Harvey Yang, Mark Baptista, Laura Doornekamp, Tessa Kerkman, John Codrington, Jimmy Roosblad, Stephen G. S. Vreden, Erwin De Bruin, Ramona Mögling, Bart C. Jacobs, Suzan D. Pas, Corine H. GeurtsvanKessel, Chantal B. E. M. Reusken, Marion P. Koopmans, Eric C. M. Van Gorp, Henk Alberga |
Abstract |
We present three patients from Suriname who were diagnosed with Guillain-Barré syndrome (GBS) during the Zika virus (ZIKV) outbreak in this country. One patient had a positive ZIKV urine real-time RT-PCR (qRT-PCR) result. The other two patients had a negative ZIKV urine qRT-PCR but a positive virus neutralization test and presence of IgG antibodies against ZIKV in the serum. Considering the evidence of a past ZIKV infection and absence of evidence for recent infections with the most common preceding infections of GBS, it is very likely that these GBS cases were triggered by ZIKV. |
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