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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Retinal Ganglion Cells and Circadian Rhythms in Alzheimer’s Disease, Parkinson’s Disease, and Beyond
|
|---|---|
| Published in |
Frontiers in Neurology, May 2017
|
| DOI | 10.3389/fneur.2017.00162 |
| Pubmed ID | |
| Authors |
Chiara La Morgia, Fred N. Ross-Cisneros, Alfredo A. Sadun, Valerio Carelli |
| Abstract |
There is increasing awareness on the role played by circadian rhythm abnormalities in neurodegenerative disorders such as Alzheimer's disease (AD) and Parkinson's disease (PD). The characterization of the circadian dysfunction parallels the mounting evidence that the hallmarks of neurodegeneration also affect the retina and frequently lead to loss of retinal ganglion cells (RGCs) and to different degrees of optic neuropathy. In the RGC population, there is the subgroup of cells intrinsically photosensitive and expressing the photopigment melanopsin [melanopsin-containing retinal ganglion cells (mRGCs)], which are now well known to drive the entrainment of circadian rhythms to the light-dark cycles. Thus, the correlation between the pathological changes affecting the retina and mRGCs with the circadian imbalance in these neurodegenerative diseases is now clearly emerging, pointing to the possibility that these patients might be amenable to and benefit from light therapy. Currently, this connection is better established for AD and PD, but the same scenario may apply to other neurodegenerative disorders, such as Huntington's disease. This review highlights similarities and differences in the retinal/circadian rhythm axis in these neurodegenerative diseases posing a working frame for future studies. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 17% |
| United States | 1 | 17% |
| Switzerland | 1 | 17% |
| Unknown | 3 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 141 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 140 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 26 | 18% |
| Researcher | 21 | 15% |
| Student > Bachelor | 17 | 12% |
| Other | 8 | 6% |
| Student > Master | 8 | 6% |
| Other | 17 | 12% |
| Unknown | 44 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 29 | 21% |
| Medicine and Dentistry | 23 | 16% |
| Agricultural and Biological Sciences | 14 | 10% |
| Biochemistry, Genetics and Molecular Biology | 8 | 6% |
| Psychology | 8 | 6% |
| Other | 12 | 9% |
| Unknown | 47 | 33% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 September 2019.
All research outputs
#2,339,751
of 23,237,082 outputs
Outputs from Frontiers in Neurology
#1,208
of 12,161 outputs
Outputs of similar age
#45,609
of 311,443 outputs
Outputs of similar age from Frontiers in Neurology
#22
of 173 outputs
Altmetric has tracked 23,237,082 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 12,161 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,443 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 173 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.