Title |
The Role of MicroRNAs in Aβ Deposition and Tau Phosphorylation in Alzheimer’s Disease
|
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Published in |
Frontiers in Neurology, July 2017
|
DOI | 10.3389/fneur.2017.00342 |
Pubmed ID | |
Authors |
Juanjuan Zhao, Dongxu Yue, Ya Zhou, Li Jia, Hairong Wang, Mengmeng Guo, Hualin Xu, Chao Chen, Jidong Zhang, Lin Xu |
Abstract |
Alzheimer's disease (AD), with main clinical features of progressive impairment in cognitive and behavioral functions, is the most common degenerative disease of the central nervous system. Recent evidence showed that microRNAs (miRNAs) played important roles in the pathological progression of AD. In this article, we reviewed the promising role of miRNAs in both Aβ deposition and Tau phosphorylation, two key pathological characters in the pathological progression of AD, which might be helpful for the understanding of pathogenesis and the development of new strategies of clinical diagnosis and treatment of AD. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 1 | 33% |
Brazil | 1 | 33% |
Switzerland | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 65 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 14 | 22% |
Student > Ph. D. Student | 14 | 22% |
Student > Bachelor | 12 | 18% |
Student > Master | 6 | 9% |
Other | 4 | 6% |
Other | 2 | 3% |
Unknown | 13 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 14 | 22% |
Biochemistry, Genetics and Molecular Biology | 11 | 17% |
Pharmacology, Toxicology and Pharmaceutical Science | 9 | 14% |
Agricultural and Biological Sciences | 6 | 9% |
Immunology and Microbiology | 3 | 5% |
Other | 6 | 9% |
Unknown | 16 | 25% |