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Laser Doppler Assessment of Vasomotor Axon Reflex Responsiveness to Evaluate Neurovascular Function

Overview of attention for article published in Frontiers in Neurology, August 2017
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Title
Laser Doppler Assessment of Vasomotor Axon Reflex Responsiveness to Evaluate Neurovascular Function
Published in
Frontiers in Neurology, August 2017
DOI 10.3389/fneur.2017.00370
Pubmed ID
Authors

Marie Luise Kubasch, Anne Sophie Kubasch, Juliana Torres Pacheco, Sylvia J. Buchmann, Ben Min-Woo Illigens, Kristian Barlinn, Timo Siepmann

Abstract

The vasomotor axon reflex can be evoked in peripheral epidermal nociceptive C-fibers to induce local vasodilation. This neurogenic flare response is a measure of C-fiber functional integrity and therefore shows impairment in patients with small fiber neuropathy. Laser Doppler flowmetry (LDF) and laser Doppler imaging (LDI) are both techniques to analyze vasomotor small fiber function by quantifying the integrity of the vasomotor-mediated axon reflex. While LDF assesses the flare response following acetylcholine iontophoresis with temporal resolution at a single defined skin point, LDI records flare responses with spatial and temporal resolution, generating a two-dimensional map of superficial blood flow. LDF is characterized by a high intra- and interindividual measurement variability, which is smaller in LDI due to its spatial resolution. Nevertheless, LDI still lacks standardized methods for image analysis. Consequently, use of the technique currently remains on an experimental level. Here, we sought to review the current literature on laser Doppler assessment of vasomotor function and discuss potential future applications of established techniques as well as those that are still experimental.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 24%
Student > Ph. D. Student 6 18%
Other 4 12%
Student > Postgraduate 3 9%
Student > Doctoral Student 2 6%
Other 5 15%
Unknown 6 18%
Readers by discipline Count As %
Medicine and Dentistry 13 38%
Neuroscience 3 9%
Engineering 2 6%
Sports and Recreations 2 6%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 3 9%
Unknown 10 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2017.
All research outputs
#18,567,744
of 22,997,544 outputs
Outputs from Frontiers in Neurology
#7,836
of 11,895 outputs
Outputs of similar age
#243,421
of 317,683 outputs
Outputs of similar age from Frontiers in Neurology
#144
of 209 outputs
Altmetric has tracked 22,997,544 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,895 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
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We're also able to compare this research output to 209 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.