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Systemic and Local Cytokine Profile following Spinal Cord Injury in Rats: A Multiplex Analysis

Overview of attention for article published in Frontiers in Neurology, October 2017
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Title
Systemic and Local Cytokine Profile following Spinal Cord Injury in Rats: A Multiplex Analysis
Published in
Frontiers in Neurology, October 2017
DOI 10.3389/fneur.2017.00581
Pubmed ID
Authors

Yana O. Mukhamedshina, Elvira R. Akhmetzyanova, Ekaterina V. Martynova, Svetlana F. Khaiboullina, Luisa R. Galieva, Albert A. Rizvanov

Abstract

Our study of the changes in cytokine profile in blood serum and in the spinal cord after traumatic spinal cord injury (SCI) has shown that an inflammatory reaction and immunological response are not limited to the CNS, but widespread. This fact was confirmed by changes detected in a cytokine profile in blood serum samples [MIP-1α, interleukin 1 (IL-1) α, IL-2, IL-5, IL-1β, MCP-1, RANTES]. There were also changes in the levels of MIP-1α, IL-1α, IL-2, IL-5, IL-18, GM-colony-stimulating factor, IL-17α, IFN-γ, IL-10, IL-13, MCP-1, and GRO KC CINC-1 in samples of the rat injured spinal cord. The results underscore the complex cytokine network imbalance exhibited after SCI and show significant changes in the concentrations of 14 cytokines/chemokines with different inflammatory and immunological activities.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 58 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 24%
Researcher 8 14%
Student > Bachelor 7 12%
Student > Master 5 9%
Student > Doctoral Student 3 5%
Other 7 12%
Unknown 14 24%
Readers by discipline Count As %
Neuroscience 22 38%
Medicine and Dentistry 6 10%
Agricultural and Biological Sciences 5 9%
Biochemistry, Genetics and Molecular Biology 3 5%
Social Sciences 2 3%
Other 5 9%
Unknown 15 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2017.
All research outputs
#20,451,228
of 23,007,053 outputs
Outputs from Frontiers in Neurology
#8,927
of 11,904 outputs
Outputs of similar age
#286,637
of 328,927 outputs
Outputs of similar age from Frontiers in Neurology
#145
of 197 outputs
Altmetric has tracked 23,007,053 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,904 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 197 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.