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Efficacy of Modified Atkins Ketogenic Diet in Chronic Cluster Headache: An Open-Label, Single-Arm, Clinical Trial

Overview of attention for article published in Frontiers in Neurology, February 2018
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  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

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70 X users
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15 Facebook pages
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3 Wikipedia pages
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1 Google+ user
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1 YouTube creator

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65 Mendeley
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Title
Efficacy of Modified Atkins Ketogenic Diet in Chronic Cluster Headache: An Open-Label, Single-Arm, Clinical Trial
Published in
Frontiers in Neurology, February 2018
DOI 10.3389/fneur.2018.00064
Pubmed ID
Authors

Cherubino Di Lorenzo, Gianluca Coppola, Davide Di Lenola, Maurizio Evangelista, Giulio Sirianni, Paolo Rossi, Giorgio Di Lorenzo, Mariano Serrao, Francesco Pierelli

Abstract

Drug-resistant cluster headache (CH) is still an open clinical challenge. Recently, our group observed the clinical efficacy of a ketogenic diet (KD), usually adopted to treat drug-resistant epilepsies, on migraine. Here, we aim to detect the effect of KD in a group of drug-resistant chronic CH (CCH) patients. Eighteen drug-resistant CCH patients underwent a 12-week KD (Modified Atkins Diet, MAD), and the clinical response was evaluated in terms of response (≥50% attack reduction). Of the 18 CCH patients, 15 were considered responders to the diet (11 experienced a full resolution of headache, and 4 had a headache reduction of at least 50% in terms of mean monthly number of attacks during the diet). The mean monthly number of attacks for each patient at the baseline was 108.71 (SD = 81.71); at the end of the third month of diet, it was reduced to 31.44 (SD = 84.61). We observed for the first time that a 3-month ketogenesis ameliorates clinical features of CCH. www.ClinicalTrials.gov, identifier NCT03244735.

X Demographics

X Demographics

The data shown below were collected from the profiles of 70 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 65 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 14%
Student > Bachelor 8 12%
Other 7 11%
Researcher 7 11%
Student > Doctoral Student 5 8%
Other 8 12%
Unknown 21 32%
Readers by discipline Count As %
Medicine and Dentistry 17 26%
Neuroscience 5 8%
Nursing and Health Professions 4 6%
Agricultural and Biological Sciences 4 6%
Biochemistry, Genetics and Molecular Biology 3 5%
Other 3 5%
Unknown 29 45%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 57. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 December 2022.
All research outputs
#745,723
of 25,349,102 outputs
Outputs from Frontiers in Neurology
#250
of 14,448 outputs
Outputs of similar age
#18,274
of 458,066 outputs
Outputs of similar age from Frontiers in Neurology
#3
of 237 outputs
Altmetric has tracked 25,349,102 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,448 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.5. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 458,066 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 237 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.