Title |
A Longitudinal Study of a Chinese Man Presenting with Non-Fluent/Agrammatic Variant of Primary Progressive Aphasia
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Published in |
Frontiers in Neurology, February 2018
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DOI | 10.3389/fneur.2018.00075 |
Pubmed ID | |
Authors |
Xiaoyan Liu, Fangping He, Zhongqin Chen, Ping Liu, Guoping Peng |
Abstract |
Primary progressive aphasia (PPA) is a neurodegenerative disease characterized by declining language ability. However, the difficulty in defining the central clinical features in its earliest stage and establishing the dynamics of its progression has led to controversy. We report a 71-year-old man with Han language suffering from non-fluent/agrammatic variant of PPA but presenting as typical Alzheimer's disease (AD) and confused with logopenic variant of PPA in its early stage, longitudinally describing his clinical characteristics, neuroanatomical basis, and genetic associations, and exploring the underlying pathology. This case highlights a longitudinal data for reliably discriminating among AD and PPA variants and helps to deepen our understanding of Han language non-fluent/agrammatic variant of PPA. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 5 | 20% |
Student > Master | 4 | 16% |
Researcher | 3 | 12% |
Lecturer | 2 | 8% |
Professor | 2 | 8% |
Other | 3 | 12% |
Unknown | 6 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Neuroscience | 6 | 24% |
Nursing and Health Professions | 5 | 20% |
Linguistics | 2 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 8% |
Medicine and Dentistry | 2 | 8% |
Other | 2 | 8% |
Unknown | 6 | 24% |