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Alpha-Synuclein: From Early Synaptic Dysfunction to Neurodegeneration

Overview of attention for article published in Frontiers in Neurology, May 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
1 news outlet
twitter
33 X users

Readers on

mendeley
242 Mendeley
citeulike
1 CiteULike
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Title
Alpha-Synuclein: From Early Synaptic Dysfunction to Neurodegeneration
Published in
Frontiers in Neurology, May 2018
DOI 10.3389/fneur.2018.00295
Pubmed ID
Authors

Veronica Ghiglieri, Valeria Calabrese, Paolo Calabresi

Abstract

Over the last two decades, many experimental and clinical studies have provided solid evidence that alpha-synuclein (α-syn), a small, natively unfolded protein, is closely related to Parkinson's disease (PD) pathology. To provide an overview on the different roles of this protein, here we propose a synopsis of seminal and recent studies that explored the many aspects of α-syn. Ranging from the physiological functions to its neurodegenerative potential, the relationship with the possible pathogenesis of PD will be discussed. Close attention will be paid on early cellular and molecular alterations associated with the presence of α-syn aggregates.

X Demographics

X Demographics

The data shown below were collected from the profiles of 33 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 242 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 242 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 42 17%
Student > Master 38 16%
Student > Bachelor 30 12%
Researcher 25 10%
Student > Postgraduate 11 5%
Other 32 13%
Unknown 64 26%
Readers by discipline Count As %
Neuroscience 57 24%
Biochemistry, Genetics and Molecular Biology 39 16%
Agricultural and Biological Sciences 24 10%
Medicine and Dentistry 15 6%
Unspecified 7 3%
Other 24 10%
Unknown 76 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 29. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2020.
All research outputs
#1,279,039
of 24,458,924 outputs
Outputs from Frontiers in Neurology
#427
of 13,511 outputs
Outputs of similar age
#28,329
of 331,243 outputs
Outputs of similar age from Frontiers in Neurology
#11
of 286 outputs
Altmetric has tracked 24,458,924 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,511 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.5. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,243 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 286 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.