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Direct Visualization of the Perforant Pathway in the Human Brain with Ex Vivo Diffusion Tensor Imaging

Overview of attention for article published in Frontiers in Human Neuroscience, May 2010
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Title
Direct Visualization of the Perforant Pathway in the Human Brain with Ex Vivo Diffusion Tensor Imaging
Published in
Frontiers in Human Neuroscience, May 2010
DOI 10.3389/fnhum.2010.00042
Pubmed ID
Authors

Jean C. Augustinack, Karl Helmer, Kristen E. Huber, Sita Kakunoori, Lilla Zöllei, Bruce Fischl

Abstract

Ex vivo magnetic resonance imaging yields high resolution images that reveal detailed cerebral anatomy and explicit cytoarchitecture in the cerebral cortex, subcortical structures, and white matter in the human brain. Our data illustrate neuroanatomical correlates of limbic circuitry with high resolution images at high field. In this report, we have studied ex vivo medial temporal lobe samples in high resolution structural MRI and high resolution diffusion MRI. Structural and diffusion MRIs were registered to each other and to histological sections stained for myelin for validation of the perforant pathway. We demonstrate probability maps and fiber tracking from diffusion tensor data that allows the direct visualization of the perforant pathway. Although it is not possible to validate the DTI data with invasive measures, results described here provide an additional line of evidence of the perforant pathway trajectory in the human brain and that the perforant pathway may cross the hippocampal sulcus.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 152 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 6 4%
France 3 2%
Netherlands 1 <1%
Hungary 1 <1%
United Kingdom 1 <1%
Brazil 1 <1%
Denmark 1 <1%
Mexico 1 <1%
Unknown 137 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 40 26%
Student > Ph. D. Student 31 20%
Professor > Associate Professor 12 8%
Student > Bachelor 10 7%
Other 8 5%
Other 30 20%
Unknown 21 14%
Readers by discipline Count As %
Neuroscience 31 20%
Medicine and Dentistry 23 15%
Agricultural and Biological Sciences 17 11%
Psychology 14 9%
Engineering 13 9%
Other 19 13%
Unknown 35 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 June 2014.
All research outputs
#20,655,488
of 25,371,288 outputs
Outputs from Frontiers in Human Neuroscience
#6,448
of 7,685 outputs
Outputs of similar age
#95,090
of 105,137 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#3
of 3 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,685 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.9. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
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