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Mendeley readers
Attention Score in Context
| Title |
The relationship between brain oscillatory activity and therapeutic effectiveness of transcranial magnetic stimulation in the treatment of major depressive disorder
|
|---|---|
| Published in |
Frontiers in Human Neuroscience, January 2013
|
| DOI | 10.3389/fnhum.2013.00037 |
| Pubmed ID | |
| Authors |
Andrew F. Leuchter, Ian A. Cook, Yi Jin, Bill Phillips |
| Abstract |
Major depressive disorder (MDD) is marked by disturbances in brain functional connectivity. This connectivity is modulated by rhythmic oscillations of brain electrical activity, which enable coordinated functions across brain regions. Oscillatory activity plays a central role in regulating thinking and memory, mood, cerebral blood flow, and neurotransmitter levels, and restoration of normal oscillatory patterns is associated with effective treatment of MDD. Repetitive transcranial magnetic stimulation (rTMS) is a robust treatment for MDD, but the mechanism of action (MOA) of its benefits for mood disorders remains incompletely understood. Benefits of rTMS have been tied to enhanced neuroplasticity in specific brain pathways. We summarize here the evidence that rTMS entrains and resets thalamocortical oscillators, normalizes regulation and facilitates reemergence of intrinsic cerebral rhythms, and through this mechanism restores normal brain function. This entrainment and resetting may be a critical step in engendering neuroplastic changes and the antidepressant effects of rTMS. It may be possible to modify the method of rTMS administration to enhance this MOA and achieve better antidepressant effectiveness. We propose that rTMS can be administered: (1) synchronized to a patient's individual alpha frequency (IAF), or synchronized rTMS (sTMS); (2) as a low magnetic field strength sinusoidal waveform; and, (3) broadly to multiple brain areas simultaneously. We present here the theory and evidence indicating that these modifications could enhance the therapeutic effectiveness of rTMS for the treatment of MDD. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 20% |
| Ecuador | 1 | 20% |
| Mexico | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Science communicators (journalists, bloggers, editors) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 191 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| Germany | 1 | <1% |
| Netherlands | 1 | <1% |
| Malaysia | 1 | <1% |
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 184 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 40 | 21% |
| Student > Ph. D. Student | 35 | 18% |
| Student > Master | 17 | 9% |
| Other | 16 | 8% |
| Student > Bachelor | 14 | 7% |
| Other | 42 | 22% |
| Unknown | 27 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 39 | 20% |
| Psychology | 33 | 17% |
| Neuroscience | 33 | 17% |
| Agricultural and Biological Sciences | 12 | 6% |
| Engineering | 8 | 4% |
| Other | 23 | 12% |
| Unknown | 43 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 May 2021.
All research outputs
#5,576,050
of 22,701,287 outputs
Outputs from Frontiers in Human Neuroscience
#2,272
of 7,125 outputs
Outputs of similar age
#58,776
of 280,695 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#334
of 862 outputs
Altmetric has tracked 22,701,287 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,125 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.5. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,695 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 862 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.