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Cortical organization of inhibition-related functions and modulation by psychopathology

Overview of attention for article published in Frontiers in Human Neuroscience, January 2013
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Title
Cortical organization of inhibition-related functions and modulation by psychopathology
Published in
Frontiers in Human Neuroscience, January 2013
DOI 10.3389/fnhum.2013.00271
Pubmed ID
Authors

Stacie L. Warren, Laura D. Crocker, Jeffery M. Spielberg, Anna S. Engels, Marie T. Banich, Bradley P. Sutton, Gregory A. Miller, Wendy Heller

Abstract

Individual differences in inhibition-related functions have been implicated as risk factors for a broad range of psychopathology, including anxiety and depression. Delineating neural mechanisms of distinct inhibition-related functions may clarify their role in the development and maintenance of psychopathology. The present study tested the hypothesis that activity in common and distinct brain regions would be associated with an ecologically sensitive, self-report measure of inhibition and a laboratory performance measure of prepotent response inhibition. Results indicated that sub-regions of DLPFC distinguished measures of inhibition, whereas left inferior frontal gyrus and bilateral inferior parietal cortex were associated with both types of inhibition. Additionally, co-occurring anxiety and depression modulated neural activity in select brain regions associated with response inhibition. Results imply that specific combinations of anxiety and depression dimensions are associated with failure to implement top-down attentional control as reflected in inefficient recruitment of posterior DLPFC and increased activation in regions associated with threat (MTG) and worry (BA10). Present findings elucidate possible neural mechanisms of interference that could help explain executive control deficits in psychopathology.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Italy 1 1%
Argentina 1 1%
Unknown 88 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 24 26%
Researcher 13 14%
Student > Master 10 11%
Student > Doctoral Student 9 10%
Professor > Associate Professor 5 5%
Other 13 14%
Unknown 17 19%
Readers by discipline Count As %
Psychology 51 56%
Neuroscience 8 9%
Medicine and Dentistry 6 7%
Engineering 4 4%
Business, Management and Accounting 1 1%
Other 3 3%
Unknown 18 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2013.
All research outputs
#15,272,977
of 22,711,645 outputs
Outputs from Frontiers in Human Neuroscience
#5,256
of 7,128 outputs
Outputs of similar age
#181,510
of 280,737 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#681
of 862 outputs
Altmetric has tracked 22,711,645 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,128 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.5. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,737 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 862 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.