↓ Skip to main content

Moderate relationships between NAA and cognitive ability in healthy adults: implications for cognitive spectroscopy

Overview of attention for article published in Frontiers in Human Neuroscience, January 2014
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
2 X users

Citations

dimensions_citation
30 Dimensions

Readers on

mendeley
40 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Moderate relationships between NAA and cognitive ability in healthy adults: implications for cognitive spectroscopy
Published in
Frontiers in Human Neuroscience, January 2014
DOI 10.3389/fnhum.2014.00039
Pubmed ID
Authors

Tulpesh Patel, Jacqueline C. Blyth, Gareth Griffiths, Deirdre Kelly, Joel B. Talcott

Abstract

Background: Proton Magnetic Resonance Spectroscopy ((1)H-MRS) is a non-invasive imaging technique that enables quantification of neurochemistry in vivo and thereby facilitates investigation of the biochemical underpinnings of human cognitive variability. Studies in the field of cognitive spectroscopy have commonly focused on relationships between measures of N-acetyl aspartate (NAA), a surrogate marker of neuronal health and function, and broad measures of cognitive performance, such as IQ. Methodology/Principal Findings: In this study, we used (1)H-MRS to interrogate single-voxels in occipitoparietal and frontal cortex, in parallel with assessments of psychometric intelligence, in a sample of 40 healthy adult participants. We found correlations between NAA and IQ that were within the range reported in previous studies. However, the magnitude of these effects was significantly modulated by the stringency of data screening and the extent to which outlying values contributed to statistical analyses. Conclusions/Significance: (1)H-MRS offers a sensitive tool for assessing neurochemistry non-invasively, yet the relationships between brain metabolites and broad aspects of human behavior such as IQ are subtle. We highlight the need to develop an increasingly rigorous analytical and interpretive framework for collecting and reporting data obtained from cognitive spectroscopy studies of this kind.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 39 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 18%
Student > Ph. D. Student 7 18%
Student > Master 5 13%
Student > Postgraduate 4 10%
Student > Doctoral Student 3 8%
Other 5 13%
Unknown 9 23%
Readers by discipline Count As %
Neuroscience 10 25%
Medicine and Dentistry 8 20%
Psychology 6 15%
Agricultural and Biological Sciences 3 8%
Engineering 2 5%
Other 0 0%
Unknown 11 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2014.
All research outputs
#15,133,846
of 24,036,420 outputs
Outputs from Frontiers in Human Neuroscience
#4,696
of 7,404 outputs
Outputs of similar age
#181,458
of 313,991 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#78
of 124 outputs
Altmetric has tracked 24,036,420 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,404 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.8. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,991 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 124 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.