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Neurorestorative Therapy for Stroke

Overview of attention for article published in Frontiers in Human Neuroscience, June 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (60th percentile)

Mentioned by

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8 X users
patent
1 patent

Readers on

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121 Mendeley
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Title
Neurorestorative Therapy for Stroke
Published in
Frontiers in Human Neuroscience, June 2014
DOI 10.3389/fnhum.2014.00382
Pubmed ID
Authors

Jieli Chen, Poornima Venkat, Alex Zacharek, Michael Chopp

Abstract

Ischemic stroke is responsible for many deaths and long-term disability world wide. Development of effective therapy has been the target of intense research. Accumulating preclinical literature has shown that substantial functional improvement after stroke can be achieved using subacutely administered cell-based and pharmacological therapies. This review will discuss some of the latest findings on bone marrow-derived mesenchymal stem cells (BMSCs), human umbilical cord blood cells, and off-label use of some pharmacological agents, to promote recovery processes in the sub-acute and chronic phases following stroke. This review paper also focuses on molecular mechanisms underlying the cell-based and pharmacological restorative processes, which enhance angiogenesis, arteriogenesis, neurogenesis, and white matter remodeling following cerebral ischemia as well as an analysis of the interaction/coupling among these restorative events. In addition, the role of microRNAs mediating the intercellular communication between exogenously administered cells and parenchymal cells, and their effects on the regulation of angiogenesis and neuronal progenitor cell proliferation and differentiation, and brain plasticity after stroke are described.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 121 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Canada 1 <1%
Unknown 119 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 19 16%
Student > Master 13 11%
Student > Bachelor 13 11%
Researcher 12 10%
Other 8 7%
Other 25 21%
Unknown 31 26%
Readers by discipline Count As %
Medicine and Dentistry 30 25%
Neuroscience 21 17%
Agricultural and Biological Sciences 15 12%
Biochemistry, Genetics and Molecular Biology 6 5%
Engineering 3 2%
Other 8 7%
Unknown 38 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2023.
All research outputs
#5,179,947
of 25,463,724 outputs
Outputs from Frontiers in Human Neuroscience
#2,149
of 7,706 outputs
Outputs of similar age
#47,298
of 242,660 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#102
of 259 outputs
Altmetric has tracked 25,463,724 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,706 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.9. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,660 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 259 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.