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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Effects of weekly low-frequency rTMS on autonomic measures in children with autism spectrum disorder
|
|---|---|
| Published in |
Frontiers in Human Neuroscience, October 2014
|
| DOI | 10.3389/fnhum.2014.00851 |
| Pubmed ID | |
| Authors |
Manuel Fernando Casanova, Marie K. Hensley, Estate M. Sokhadze, Ayman S. El-Baz, Yao Wang, Xiaoli Li, Lonnie Sears |
| Abstract |
The term autism spectrum disorder (ASD) describes a range of conditions characterized by impairments in social interactions, communication, and by restricted and repetitive behaviors. Autism spectrum disorder may also present with symptoms suggestive of autonomic nervous system (ANS) dysfunction. The objective of this study was to determine the effect of 18 sessions of low frequency (LF) repetitive transcranial magnetic stimulation (rTMS) on autonomic function in children with ASD by recording electrocardiogram (ECG) and electrodermal activity (EDA) pre- post- and during each rTMS session. The autonomic measures of interest in this study were R-R cardiointervals in EKG (R-R), time and frequency domain measures of heart rate variability (HRV) and skin conductance level (SCL). Heart rate variability measures such as R-R intervals, standard deviation of cardiac intervals, pNN50 (percentage of cardiointervals >50 ms different from preceding interval), power of high frequency (HF) and LF components of HRV spectrum, LF/HF ratio, were then derived from the recorded EKG. We expected that the course of 18 weekly inhibitory LF rTMS applied to the dorsolateral prefrontal cortex (DLPFC) would enhance autonomic balance by facilitating frontal inhibition of limbic activity thus resulting in decreased overall heart rate (HR), increased HRV (in a form of increased HF power), decreased LF power (resulting in decreased LF/HF ratio), and decreased SCL. Behavioral evaluations post-18 TMS showed decreased irritability, hyperactivity, stereotype behavior and compulsive behavior ratings while autonomic measures indicated a significant increase in cardiac interval variability and a decrease of tonic SCL. The results suggest that 18 sessions of LF rTMS in ASD results in increased cardiac vagal control and reduced sympathetic arousal. |
X Demographics
The data shown below were collected from the profiles of 10 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 8 | 80% |
| North Macedonia | 1 | 10% |
| Unknown | 1 | 10% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 70% |
| Scientists | 2 | 20% |
| Practitioners (doctors, other healthcare professionals) | 1 | 10% |
Mendeley readers
The data shown below were compiled from readership statistics for 166 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Finland | 1 | <1% |
| India | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 163 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 31 | 19% |
| Student > Ph. D. Student | 19 | 11% |
| Student > Bachelor | 16 | 10% |
| Researcher | 14 | 8% |
| Student > Doctoral Student | 9 | 5% |
| Other | 35 | 21% |
| Unknown | 42 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 37 | 22% |
| Medicine and Dentistry | 20 | 12% |
| Neuroscience | 20 | 12% |
| Agricultural and Biological Sciences | 9 | 5% |
| Arts and Humanities | 5 | 3% |
| Other | 22 | 13% |
| Unknown | 53 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2015.
All research outputs
#4,281,248
of 25,654,806 outputs
Outputs from Frontiers in Human Neuroscience
#1,886
of 7,741 outputs
Outputs of similar age
#46,240
of 273,681 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#75
of 243 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,741 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 273,681 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 243 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.