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Simultaneous tDCS-fMRI Identifies Resting State Networks Correlated with Visual Search Enhancement

Overview of attention for article published in Frontiers in Human Neuroscience, March 2016
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Title
Simultaneous tDCS-fMRI Identifies Resting State Networks Correlated with Visual Search Enhancement
Published in
Frontiers in Human Neuroscience, March 2016
DOI 10.3389/fnhum.2016.00072
Pubmed ID
Authors

Daniel E. Callan, Brian Falcone, Atsushi Wada, Raja Parasuraman

Abstract

This study uses simultaneous transcranial direct current stimulation (tDCS) and functional MRI (fMRI) to investigate tDCS modulation of resting state activity and connectivity that underlies enhancement in behavioral performance. The experiment consisted of three sessions within the fMRI scanner in which participants conducted a visual search task: Session 1: Pre-training (no performance feedback), Session 2: Training (performance feedback given), Session 3: Post-training (no performance feedback). Resting state activity was recorded during the last 5 min of each session. During the 2nd session one group of participants underwent 1 mA tDCS stimulation and another underwent sham stimulation over the right posterior parietal cortex. Resting state spontaneous activity, as measured by fractional amplitude of low frequency fluctuations (fALFF), for session 2 showed significant differences between the tDCS stim and sham groups in the precuneus. Resting state functional connectivity from the precuneus to the substantia nigra, a subcortical dopaminergic region, was found to correlate with future improvement in visual search task performance for the stim over the sham group during active stimulation in session 2. The after-effect of stimulation on resting state functional connectivity was measured following a post-training experimental session (session 3). The left cerebellum Lobule VIIa Crus I showed performance related enhancement in resting state functional connectivity for the tDCS stim over the sham group. The ability to determine the relationship that the relative strength of resting state functional connectivity for an individual undergoing tDCS has on future enhancement in behavioral performance has wide ranging implications for neuroergonomic as well as therapeutic, and rehabilitative applications.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 161 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Sweden 1 <1%
United Kingdom 1 <1%
Canada 1 <1%
China 1 <1%
United States 1 <1%
Unknown 156 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 33 20%
Researcher 27 17%
Student > Master 19 12%
Student > Bachelor 18 11%
Student > Doctoral Student 10 6%
Other 17 11%
Unknown 37 23%
Readers by discipline Count As %
Psychology 42 26%
Neuroscience 31 19%
Medicine and Dentistry 14 9%
Engineering 10 6%
Social Sciences 5 3%
Other 14 9%
Unknown 45 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2017.
All research outputs
#14,248,391
of 22,846,662 outputs
Outputs from Frontiers in Human Neuroscience
#4,594
of 7,162 outputs
Outputs of similar age
#157,528
of 298,958 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#110
of 159 outputs
Altmetric has tracked 22,846,662 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,162 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,958 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 159 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.