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fMRI Adaptation between Action Observation and Action Execution Reveals Cortical Areas with Mirror Neuron Properties in Human BA 44/45

Overview of attention for article published in Frontiers in Human Neuroscience, February 2016
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Title
fMRI Adaptation between Action Observation and Action Execution Reveals Cortical Areas with Mirror Neuron Properties in Human BA 44/45
Published in
Frontiers in Human Neuroscience, February 2016
DOI 10.3389/fnhum.2016.00078
Pubmed ID
Authors

Stephan de la Rosa, Frieder L. Schillinger, Heinrich H. Bülthoff, Johannes Schultz, Kamil Uludag

Abstract

Mirror neurons (MNs) are considered to be the supporting neural mechanism for action understanding. MNs have been identified in monkey's area F5. The identification of MNs in the human homolog of monkeys' area F5 Broadmann Area 44/45 (BA 44/45) has been proven methodologically difficult. Cross-modal functional MRI (fMRI) adaptation studies supporting the existence of MNs restricted their analysis to a priori candidate regions, whereas studies that failed to find evidence used non-object-directed (NDA) actions. We tackled these limitations by using object-directed actions (ODAs) differing only in terms of their object directedness in combination with a cross-modal adaptation paradigm and a whole-brain analysis. Additionally, we tested voxels' blood oxygenation level-dependent (BOLD) response patterns for several properties previously reported as typical MN response properties. Our results revealed 52 voxels in left inferior frontal gyrus (IFG; particularly BA 44/45), which respond to both motor and visual stimulation and exhibit cross-modal adaptation between the execution and observation of the same action. These results demonstrate that part of human IFG, specifically BA 44/45, has BOLD response characteristics very similar to monkey's area F5.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 75 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 22 29%
Student > Master 12 16%
Student > Bachelor 11 15%
Researcher 9 12%
Professor 5 7%
Other 9 12%
Unknown 7 9%
Readers by discipline Count As %
Psychology 25 33%
Neuroscience 19 25%
Medicine and Dentistry 5 7%
Agricultural and Biological Sciences 4 5%
Social Sciences 3 4%
Other 7 9%
Unknown 12 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 February 2016.
All research outputs
#13,517,981
of 23,323,574 outputs
Outputs from Frontiers in Human Neuroscience
#3,881
of 7,265 outputs
Outputs of similar age
#140,418
of 298,778 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#86
of 157 outputs
Altmetric has tracked 23,323,574 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,265 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,778 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 157 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.