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Central Neural Correlates During Inhibitory Control in Lifelong Premature Ejaculation Patients

Overview of attention for article published in Frontiers in Human Neuroscience, May 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (78th percentile)
  • Good Attention Score compared to outputs of the same age and source (74th percentile)

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Title
Central Neural Correlates During Inhibitory Control in Lifelong Premature Ejaculation Patients
Published in
Frontiers in Human Neuroscience, May 2018
DOI 10.3389/fnhum.2018.00206
Pubmed ID
Authors

Xuejuan Yang, Ming Gao, Lan Zhang, Lin Liu, Peng Liu, Jinbo Sun, Yibin Xi, Hong Yin, Wei Qin

Abstract

Lifelong premature ejaculation (LPE) is a common male sexual dysfunction. Lack of active control for rapid ejaculation brought great distress to sexual harmony and even fertility. Previous neurophysiology studies revealed an ejaculation-related control mechanism in the brain. However, it remains unclear whether this inhibitory network is altered in LPE patients. The present study investigated the central inhibitory network function of LPE patients by using stop signal task (SST)-related functional magnetic resonance imaging (fMRI) and resting-state functional connectivity (FC) analysis. The results showed no difference in task-related behavioral performance or neural activation during response inhibition between LPE patients and controls. However, LPE patients showed a significantly different correlation pattern between the stop signal reaction time (SSRT) and left inferior frontal gyrus (IFG) activation during successful inhibition, in which a typical negative correlation between SSRT and the activation was completely disappeared in patients. In addition, using the left IFG as a seed, patients showed weaker FC between the seed and two areas (left dentate nucleus (DN) and right frontal pole) compared with controls. These data suggest that LPE patients have an abnormal brain control network, which may contribute to the reduced central control of rapid ejaculation. This study provides new insights into the neural mechanism of LPE involving the central inhibitory network, which may offer an underlying intervention target for future treatment.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 28%
Researcher 5 20%
Student > Master 4 16%
Student > Bachelor 2 8%
Student > Doctoral Student 2 8%
Other 2 8%
Unknown 3 12%
Readers by discipline Count As %
Psychology 9 36%
Neuroscience 4 16%
Medicine and Dentistry 3 12%
Sports and Recreations 2 8%
Nursing and Health Professions 1 4%
Other 2 8%
Unknown 4 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 June 2018.
All research outputs
#3,600,926
of 23,045,021 outputs
Outputs from Frontiers in Human Neuroscience
#1,683
of 7,200 outputs
Outputs of similar age
#70,915
of 330,046 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#35
of 141 outputs
Altmetric has tracked 23,045,021 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,200 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,046 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 141 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.