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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Fine-Tuning Oligodendrocyte Development by microRNAs
|
|---|---|
| Published in |
Frontiers in Neuroscience, January 2012
|
| DOI | 10.3389/fnins.2012.00013 |
| Pubmed ID | |
| Authors |
Olga Barca-Mayo, Q. Richard Lu |
| Abstract |
Myelination of axons by oligodendrocytes in the central nervous system is essential for normal neuronal functions. The failure of remyelination due to injury or pathological insults results in devastating demyelinating diseases. Oligodendrocytes originate in restricted regions of the embryonic ventral neural tube. After migration to populate all areas of the brain and spinal cord, oligodendrocyte precursors undergo a temporally well-defined series of molecular and structural changes, ultimately culminating in the cessation of proliferation, and the elaboration of a highly complex myelin sheath. The emergence of microRNAs (miRNAs) as potent regulators of gene expression at the posttranscriptional level has broad implications in all facets of cell biology. Recent studies have demonstrated a critical role of miRNAs in oligodendrocyte development, including cell proliferation, differentiation, and myelin formation. In this review, we will highlight and discuss the recent understanding of functional links of miRNAs to regulatory networks for central myelination, as well as perspectives on the role of miRNAs in demyelinating diseases. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | <1% |
| Chile | 1 | <1% |
| Sweden | 1 | <1% |
| France | 1 | <1% |
| Unknown | 125 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 30 | 23% |
| Student > Ph. D. Student | 25 | 19% |
| Student > Master | 21 | 16% |
| Student > Bachelor | 14 | 11% |
| Student > Postgraduate | 11 | 9% |
| Other | 19 | 15% |
| Unknown | 9 | 7% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 49 | 38% |
| Neuroscience | 21 | 16% |
| Medicine and Dentistry | 18 | 14% |
| Biochemistry, Genetics and Molecular Biology | 17 | 13% |
| Immunology and Microbiology | 2 | 2% |
| Other | 7 | 5% |
| Unknown | 15 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 March 2018.
All research outputs
#5,240,751
of 25,374,917 outputs
Outputs from Frontiers in Neuroscience
#3,988
of 11,541 outputs
Outputs of similar age
#41,226
of 250,099 outputs
Outputs of similar age from Frontiers in Neuroscience
#44
of 154 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,541 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one has gotten more attention than average, scoring higher than 65% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,099 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.