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The Tale of the Three Brothers – Shh, Wnt, and Fgf during Development of the Thalamus

Overview of attention for article published in Frontiers in Neuroscience, January 2012
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Title
The Tale of the Three Brothers – Shh, Wnt, and Fgf during Development of the Thalamus
Published in
Frontiers in Neuroscience, January 2012
DOI 10.3389/fnins.2012.00076
Pubmed ID
Authors

Anja I. H. Hagemann, Steffen Scholpp

Abstract

The thalamic complex is an essential part of the brain that requires a combination of specialized activities to attain its final complexity. In the following review we will describe the induction process of the mid-diencephalic organizer (MDO) where three different signaling pathways merge: Wnt, Shh, and Fgf. Here, we dissect the function of each signaling pathway in the thalamus in chronological order of their appearance. First we describe the Wnt mediated induction of the MDO and compartition of the caudal forebrain, then the Shh mediated determination of proneural gene expression before discussing recent progress in characterizing Fgf function during thalamus development. Then, we focus on transcription factors, which are regulated by these pathways and which play a pivotal role in neurogenesis in the thalamus. The three signaling pathways act together in a strictly regulated chronology to orchestrate the development of the entire thalamus.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 3%
United Kingdom 2 3%
Spain 2 3%
Belgium 1 1%
Germany 1 1%
Japan 1 1%
Croatia 1 1%
Unknown 67 87%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 32%
Student > Master 13 17%
Researcher 9 12%
Student > Bachelor 8 10%
Student > Postgraduate 3 4%
Other 6 8%
Unknown 13 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 35 45%
Biochemistry, Genetics and Molecular Biology 11 14%
Neuroscience 7 9%
Medicine and Dentistry 4 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 6 8%
Unknown 12 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 July 2021.
All research outputs
#16,046,765
of 25,373,627 outputs
Outputs from Frontiers in Neuroscience
#7,061
of 11,538 outputs
Outputs of similar age
#163,292
of 250,087 outputs
Outputs of similar age from Frontiers in Neuroscience
#96
of 154 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,538 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,087 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.