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Recent Insights into the Role of Hypothalamic AMPK Signaling Cascade upon Metabolic Control

Overview of attention for article published in Frontiers in Neuroscience, January 2012
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Title
Recent Insights into the Role of Hypothalamic AMPK Signaling Cascade upon Metabolic Control
Published in
Frontiers in Neuroscience, January 2012
DOI 10.3389/fnins.2012.00185
Pubmed ID
Authors

Marc Schneeberger, Marc Claret

Abstract

In 2004, two seminal papers focused on the role of AMP-activated protein kinase (AMPK) in the hypothalamus opened new avenues of research in the field of the central regulation of energy homeostasis. Over the following 8 years, hundreds of studies have firmly established hypothalamic AMPK as a key sensor and integrator of hormonal and nutritional signals with neurochemical and neurophysiological responses to regulate whole-body energy balance. In this review article we aim to discuss the most recent findings in this particular area of research, highlighting the function of hypothalamic AMPK in appetite, thermogenesis, and peripheral glucose metabolism. The diversity of mechanisms by which hypothalamic AMPK regulates energy homeostasis illustrates the importance of this evolutionary-conserved energy signaling cascade in the control of this complex and fundamental biological process.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 2%
Unknown 56 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 21%
Student > Bachelor 9 16%
Researcher 8 14%
Professor > Associate Professor 7 12%
Student > Doctoral Student 4 7%
Other 6 11%
Unknown 11 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 26%
Biochemistry, Genetics and Molecular Biology 12 21%
Medicine and Dentistry 9 16%
Neuroscience 6 11%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 3 5%
Unknown 10 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 December 2016.
All research outputs
#19,942,887
of 25,371,288 outputs
Outputs from Frontiers in Neuroscience
#8,668
of 11,538 outputs
Outputs of similar age
#199,366
of 250,087 outputs
Outputs of similar age from Frontiers in Neuroscience
#117
of 154 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,538 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
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We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.