Title |
Functional mapping of thalamic nuclei and their integration into cortico-striatal-thalamo-cortical loops via ultra-high resolution imaging—from animal anatomy to in vivo imaging in humans
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Published in |
Frontiers in Neuroscience, January 2013
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DOI | 10.3389/fnins.2013.00024 |
Pubmed ID | |
Authors |
Coraline D. Metzger, Ysbrand D. van der Werf, Martin Walter |
Abstract |
The thalamus, a crucial node in the well-described cortico-striatal-thalamo-cortical circuits, has been the focus of functional and structural imaging studies investigating human emotion, cognition and memory. Invasive work in animals and post-mortem investigations have revealed the rich cytoarchitectonics and functional specificity of the thalamus. Given current restrictions in the spatial resolution of non-invasive imaging modalities, there is, however, a translational gap between functional and structural information on these circuits in humans and animals as well as between histological and cellular evidence and their relationship to psychological functioning. With the advance of higher field strengths for MR approaches, better spatial resolution is now available promising to overcome this conceptual problem. We here review these two levels, which exist for both neuroscientific and clinical investigations, and then focus on current attempts to overcome conceptual boundaries of these observations with the help of ultra-high resolution imaging. |
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Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 33% |
United States | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
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Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 3 | 2% |
Switzerland | 2 | 2% |
Netherlands | 1 | <1% |
Chile | 1 | <1% |
Germany | 1 | <1% |
France | 1 | <1% |
Canada | 1 | <1% |
Spain | 1 | <1% |
United States | 1 | <1% |
Other | 0 | 0% |
Unknown | 113 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 36 | 29% |
Student > Ph. D. Student | 30 | 24% |
Student > Master | 14 | 11% |
Student > Bachelor | 10 | 8% |
Other | 8 | 6% |
Other | 18 | 14% |
Unknown | 9 | 7% |
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Neuroscience | 28 | 22% |
Psychology | 23 | 18% |
Medicine and Dentistry | 22 | 18% |
Agricultural and Biological Sciences | 16 | 13% |
Engineering | 8 | 6% |
Other | 10 | 8% |
Unknown | 18 | 14% |