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Autism spectrum disorder in children born preterm—role of exposure to perinatal inflammation

Overview of attention for article published in Frontiers in Neuroscience, January 2013
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Title
Autism spectrum disorder in children born preterm—role of exposure to perinatal inflammation
Published in
Frontiers in Neuroscience, January 2013
DOI 10.3389/fnins.2013.00123
Pubmed ID
Authors

Suzanne J. Meldrum, T. Strunk, A. Currie, S. L. Prescott, K. Simmer, A. J. O. Whitehouse

Abstract

Autism Spectrum Disorder (ASD) is the collective term for neurodevelopmental disorders characterized by qualitative impairments in social interaction, communication, and a restricted range of activities and interests. Many countries, including Australia, have reported a dramatic increase in the number of diagnoses over the past three decades, with current prevalence of ASD at 1 in every 110 individuals (~1%). The potential role for an immune-mediated mechanism in ASD has been implicated by several studies, and some evidence suggests a potential link between prenatal infection-driven inflammation and subsequent development of ASD. Furthermore, a modest number of contemporary studies have reported a markedly increased prevalence of ASD in children born preterm, who are at highest risk of exposure to perinatal inflammation. However, the mechanisms that underpin the susceptibility to infection-driven inflammation during pregnancy and risk of preterm birth, and how these intersect with the subsequent development of ASD in the offspring, is not understood. This review aims to summarize and discuss the potential mechanisms and evidence for the role of prenatal infection on the central nervous system, and how it may increase the susceptibility for ASD pathogenesis in children born preterm.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 3%
Netherlands 1 <1%
Unknown 115 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 15%
Student > Ph. D. Student 16 13%
Researcher 13 11%
Student > Doctoral Student 12 10%
Student > Postgraduate 12 10%
Other 29 24%
Unknown 19 16%
Readers by discipline Count As %
Medicine and Dentistry 26 22%
Psychology 23 19%
Neuroscience 12 10%
Agricultural and Biological Sciences 9 8%
Biochemistry, Genetics and Molecular Biology 5 4%
Other 18 15%
Unknown 26 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2015.
All research outputs
#15,739,010
of 25,373,627 outputs
Outputs from Frontiers in Neuroscience
#6,686
of 11,538 outputs
Outputs of similar age
#177,354
of 288,986 outputs
Outputs of similar age from Frontiers in Neuroscience
#133
of 246 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,538 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,986 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 246 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.