Title |
Temporal features of adult neurogenesis: differences and similarities across mammalian species
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Published in |
Frontiers in Neuroscience, January 2013
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DOI | 10.3389/fnins.2013.00135 |
Pubmed ID | |
Authors |
Maïna Brus, Matthieu Keller, Frédéric Lévy |
Abstract |
Production of new neurons continues throughout life in most invertebrates and vertebrates like crustaceans, fishes, reptiles, birds, and mammals including humans. Most studies have been carried out on rodent models and demonstrated that adult neurogenesis is located mainly in two structures, the dentate gyrus (DG) of the hippocampus and the sub-ventricular zone (SVZ). If adult neurogenesis is well preserved throughout evolution, yet there are however some features which differ between species. The present review proposes to target similarities and differences in the mechanism of mammalian adult neurogenesis by comparing selected species including humans. We will highlight the cellular composition and morphological organization of the SVZ in primates which differs from that of rodents and may be of functional relevance. We will particularly focus on the dynamic of neuronal maturation in rodents, primates, and humans but also in sheep which appears to be an interesting model due to its similarities with the primate brain. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
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Scientists | 2 | 67% |
Members of the public | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Germany | 2 | 2% |
Switzerland | 1 | <1% |
Greece | 1 | <1% |
United States | 1 | <1% |
Poland | 1 | <1% |
Unknown | 103 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 22 | 20% |
Researcher | 17 | 16% |
Student > Master | 17 | 16% |
Student > Bachelor | 9 | 8% |
Student > Doctoral Student | 6 | 6% |
Other | 20 | 18% |
Unknown | 18 | 17% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 40 | 37% |
Neuroscience | 28 | 26% |
Medicine and Dentistry | 7 | 6% |
Biochemistry, Genetics and Molecular Biology | 6 | 6% |
Psychology | 3 | 3% |
Other | 5 | 5% |
Unknown | 20 | 18% |