You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Histone-acetylation: a link between Alzheimer's disease and post-traumatic stress disorder?
|
|---|---|
| Published in |
Frontiers in Neuroscience, June 2014
|
| DOI | 10.3389/fnins.2014.00160 |
| Pubmed ID | |
| Authors |
Sanaz Bahari-Javan, Farahnaz Sananbenesi, Andre Fischer |
| Abstract |
The orchestration of gene-expression programs is essential for cellular homeostasis. Epigenetic processes provide to the cell a key mechanism that allows the regulation of gene-expression networks in response to environmental stimuli. Recently epigenetic mechanisms such as histone-modifications have been implicated with cognitive function and altered epigenome plasticity has been linked to the pathogenesis of neurodegenerative and neuropsychiatric diseases. Thus, key regulators of epigenetic gene-expression have emerged as novel drug targets for brain diseases. Numerous recent review articles discuss in detail the current findings of epigenetic processes in brain diseases. The aim of this article is not to give yet another comprehensive overview of the field but to specifically address the question why the same epigenetic therapies that target histone-acetylation may be suitable to treat seemingly different diseases such as Alzheimer's disease and post-traumatic stress disorder. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 20% |
| France | 1 | 20% |
| Switzerland | 1 | 20% |
| Unknown | 2 | 40% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Scientists | 1 | 20% |
| Science communicators (journalists, bloggers, editors) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Netherlands | 1 | <1% |
| France | 1 | <1% |
| Uganda | 1 | <1% |
| India | 1 | <1% |
| Ireland | 1 | <1% |
| Russia | 1 | <1% |
| United Kingdom | 1 | <1% |
| Unknown | 106 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 20 | 17% |
| Researcher | 18 | 16% |
| Student > Bachelor | 15 | 13% |
| Student > Master | 14 | 12% |
| Student > Doctoral Student | 6 | 5% |
| Other | 14 | 12% |
| Unknown | 28 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 28 | 24% |
| Neuroscience | 17 | 15% |
| Biochemistry, Genetics and Molecular Biology | 13 | 11% |
| Psychology | 7 | 6% |
| Medicine and Dentistry | 6 | 5% |
| Other | 14 | 12% |
| Unknown | 30 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 July 2017.
All research outputs
#14,913,921
of 25,373,627 outputs
Outputs from Frontiers in Neuroscience
#6,086
of 11,538 outputs
Outputs of similar age
#121,087
of 243,030 outputs
Outputs of similar age from Frontiers in Neuroscience
#49
of 123 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,538 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,030 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 123 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.