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A review of β-amyloid neuroimaging in Alzheimer's disease

Overview of attention for article published in Frontiers in Neuroscience, October 2014
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  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (59th percentile)

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7 X users

Citations

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82 Dimensions

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227 Mendeley
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Title
A review of β-amyloid neuroimaging in Alzheimer's disease
Published in
Frontiers in Neuroscience, October 2014
DOI 10.3389/fnins.2014.00327
Pubmed ID
Authors

Paul A. Adlard, Bob A. Tran, David I. Finkelstein, Patricia M. Desmond, Leigh A. Johnston, Ashley I. Bush, Gary F. Egan

Abstract

Alzheimer's disease (AD) is the most common cause of dementia worldwide. As advancing age is the greatest risk factor for developing AD, the number of those afflicted is expected to increase markedly with the aging of the world's population. The inability to definitively diagnose AD until autopsy remains an impediment to establishing effective targeted treatments. Neuroimaging has enabled in vivo visualization of pathological changes in the brain associated with the disease, providing a greater understanding of its pathophysiological development and progression. However, neuroimaging biomarkers do not yet offer clear advantages over current clinical diagnostic criteria for them to be accepted into routine clinical use. Nonetheless, current insights from neuroimaging combined with the elucidation of biochemical and molecular processes in AD are informing the ongoing development of new imaging techniques and their application. Much of this research has been greatly assisted by the availability of transgenic mouse models of AD. In this review we summarize the main efforts of neuroimaging in AD in humans and in mouse models, with a specific focus on β-amyloid, and discuss the potential of new applications and novel approaches.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 227 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
United Kingdom 2 <1%
Italy 1 <1%
Germany 1 <1%
Korea, Republic of 1 <1%
Austria 1 <1%
Unknown 218 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 43 19%
Researcher 42 19%
Student > Master 33 15%
Student > Bachelor 26 11%
Student > Doctoral Student 12 5%
Other 37 16%
Unknown 34 15%
Readers by discipline Count As %
Neuroscience 36 16%
Medicine and Dentistry 35 15%
Agricultural and Biological Sciences 26 11%
Biochemistry, Genetics and Molecular Biology 19 8%
Chemistry 16 7%
Other 52 23%
Unknown 43 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 November 2014.
All research outputs
#7,688,662
of 25,374,647 outputs
Outputs from Frontiers in Neuroscience
#4,846
of 11,538 outputs
Outputs of similar age
#80,220
of 274,544 outputs
Outputs of similar age from Frontiers in Neuroscience
#48
of 119 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 11,538 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,544 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 119 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.