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Cytokine variations and mood disorders: influence of social stressors and social support

Overview of attention for article published in Frontiers in Neuroscience, December 2014
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (76th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

Mentioned by

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9 X users
facebook
2 Facebook pages

Citations

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41 Dimensions

Readers on

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143 Mendeley
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Title
Cytokine variations and mood disorders: influence of social stressors and social support
Published in
Frontiers in Neuroscience, December 2014
DOI 10.3389/fnins.2014.00416
Pubmed ID
Authors

Marie-Claude Audet, Robyn J. McQuaid, Zul Merali, Hymie Anisman

Abstract

Stressful events have been implicated in the evolution of mood disorders. In addition to brain neurotransmitters and growth factors, the view has been offered that these disorders might be provoked by the activation of the inflammatory immune system as well as by de novo changes of inflammatory cytokines within the brain. The present review describes the impact of social stressors in animals and in humans on behavioral changes reminiscent of depressive states as well as on cytokine functioning. Social stressors increase pro-inflammatory cytokines in circulation as well as in brain regions that have been associated with depression, varying with the animal's social status and/or behavioral methods used to contend with social challenges. Likewise, in humans, social stressors that favor the development of depression are accompanied by elevated circulating cytokine levels and conversely, conditions that limit the cytokine elevations correlated with symptom attenuation or reversal. The implications of these findings are discussed in relation to the potentially powerful effects of social support, social identity, and connectedness in maintaining well-being and in diminishing symptoms of depression.

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 143 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
United States 1 <1%
Portugal 1 <1%
Brazil 1 <1%
Unknown 139 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 14%
Student > Bachelor 18 13%
Researcher 17 12%
Student > Master 17 12%
Student > Doctoral Student 9 6%
Other 29 20%
Unknown 33 23%
Readers by discipline Count As %
Medicine and Dentistry 25 17%
Psychology 25 17%
Neuroscience 21 15%
Agricultural and Biological Sciences 11 8%
Biochemistry, Genetics and Molecular Biology 6 4%
Other 13 9%
Unknown 42 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2016.
All research outputs
#6,875,368
of 25,373,627 outputs
Outputs from Frontiers in Neuroscience
#4,444
of 11,538 outputs
Outputs of similar age
#84,968
of 360,776 outputs
Outputs of similar age from Frontiers in Neuroscience
#50
of 118 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 11,538 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,776 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 118 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.