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Neuronal migration and protein kinases

Overview of attention for article published in Frontiers in Neuroscience, January 2015
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Title
Neuronal migration and protein kinases
Published in
Frontiers in Neuroscience, January 2015
DOI 10.3389/fnins.2014.00458
Pubmed ID
Authors

Toshio Ohshima

Abstract

The formation of the six-layered structure of the mammalian cortex via the inside-out pattern of neuronal migration is fundamental to neocortical functions. Extracellular cues such as Reelin induce intracellular signaling cascades through the protein phosphorylation. Migrating neurons also have intrinsic machineries to regulate cytoskeletal proteins and adhesion properties. Protein phosphorylation regulates these processes. Moreover, the balance between phosphorylation and dephosphorylation is modified by extracellular cues. Multipolar-bipolar transition, radial glia-guided locomotion and terminal translocation are critical steps of radial migration of cortical pyramidal neurons. Protein kinases such as Cyclin-dependent kinase 5 (Cdk5) and c-Jun N-terminal kinases (JNKs) involve these steps. In this review, I shall give an overview the roles of protein kinases in neuronal migration.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Spain 1 1%
Unknown 68 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 18 25%
Student > Ph. D. Student 12 17%
Student > Bachelor 11 15%
Student > Master 6 8%
Other 4 6%
Other 9 13%
Unknown 11 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 37%
Neuroscience 14 20%
Biochemistry, Genetics and Molecular Biology 11 15%
Medicine and Dentistry 3 4%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 1 1%
Unknown 14 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 January 2015.
All research outputs
#19,945,185
of 25,374,917 outputs
Outputs from Frontiers in Neuroscience
#8,670
of 11,541 outputs
Outputs of similar age
#253,318
of 360,428 outputs
Outputs of similar age from Frontiers in Neuroscience
#100
of 125 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,541 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 360,428 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 125 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.