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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Therapeutic potential of mGluR5 targeting in Alzheimer's disease
|
|---|---|
| Published in |
Frontiers in Neuroscience, June 2015
|
| DOI | 10.3389/fnins.2015.00215 |
| Pubmed ID | |
| Authors |
Anil Kumar, Dinesh K. Dhull, Pooja S. Mishra |
| Abstract |
Decades of research dedicated toward Alzheimer's disease (AD) has culminated in much of the current understanding of the neurodegeneration associated with disease. However, delineating the pathophysiology and finding a possible cure for the disease is still wanting. This is in part due to the lack of knowledge pertaining to the connecting link between neurodegenerative and neuroinflammatory pathways. Consequently, the inefficacy and ill-effects of the drugs currently available for AD encourage the need for alternative and safe therapeutic intervention. In this review we highlight the potential of mGluR5, a metabotropic glutamatergic receptor, in understanding the mechanism underlying the neuronal death and neuroinflammation in AD. We also discuss the role of mGlu5 receptor in mediating the neuron-glia interaction in the disease. Finally, we discuss the potential of mGluR5 as target for treating AD. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 20% |
| Canada | 1 | 20% |
| India | 1 | 20% |
| Switzerland | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 60% |
| Scientists | 2 | 40% |
Mendeley readers
The data shown below were compiled from readership statistics for 96 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 94 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 22% |
| Researcher | 16 | 17% |
| Student > Bachelor | 13 | 14% |
| Student > Master | 7 | 7% |
| Other | 5 | 5% |
| Other | 14 | 15% |
| Unknown | 20 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 24 | 25% |
| Agricultural and Biological Sciences | 20 | 21% |
| Biochemistry, Genetics and Molecular Biology | 8 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 6% |
| Engineering | 4 | 4% |
| Other | 11 | 11% |
| Unknown | 23 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 June 2015.
All research outputs
#2,745,914
of 25,374,917 outputs
Outputs from Frontiers in Neuroscience
#1,732
of 11,541 outputs
Outputs of similar age
#34,169
of 280,070 outputs
Outputs of similar age from Frontiers in Neuroscience
#14
of 106 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,541 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,070 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.