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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Noradrenergic dysfunction in Alzheimer's disease
|
|---|---|
| Published in |
Frontiers in Neuroscience, June 2015
|
| DOI | 10.3389/fnins.2015.00220 |
| Pubmed ID | |
| Authors |
Mary Gannon, Pulin Che, Yunjia Chen, Kai Jiao, Erik D. Roberson, Qin Wang |
| Abstract |
The brain noradrenergic system supplies the neurotransmitter norepinephrine throughout the brain via widespread efferent projections, and plays a pivotal role in modulating cognitive activities in the cortex. Profound noradrenergic degeneration in Alzheimer's disease (AD) patients has been observed for decades, with recent research suggesting that the locus coeruleus (where noradrenergic neurons are mainly located) is a predominant site where AD-related pathology begins. Mounting evidence indicates that the loss of noradrenergic innervation greatly exacerbates AD pathogenesis and progression, although the precise roles of noradrenergic components in AD pathogenesis remain unclear. The aim of this review is to summarize current findings on noradrenergic dysfunction in AD, as well as to point out deficiencies in our knowledge where more research is needed. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 75% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 190 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| France | 1 | <1% |
| Unknown | 188 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 37 | 19% |
| Student > Bachelor | 26 | 14% |
| Researcher | 25 | 13% |
| Student > Master | 23 | 12% |
| Other | 9 | 5% |
| Other | 26 | 14% |
| Unknown | 44 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 41 | 22% |
| Agricultural and Biological Sciences | 23 | 12% |
| Medicine and Dentistry | 22 | 12% |
| Biochemistry, Genetics and Molecular Biology | 11 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 11 | 6% |
| Other | 27 | 14% |
| Unknown | 55 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 July 2015.
All research outputs
#2,827,603
of 25,373,627 outputs
Outputs from Frontiers in Neuroscience
#1,847
of 11,538 outputs
Outputs of similar age
#34,927
of 277,747 outputs
Outputs of similar age from Frontiers in Neuroscience
#13
of 110 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,538 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 277,747 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.