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Targeting Neural Endophenotypes of Eating Disorders with Non-invasive Brain Stimulation

Overview of attention for article published in Frontiers in Neuroscience, February 2016
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  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

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Title
Targeting Neural Endophenotypes of Eating Disorders with Non-invasive Brain Stimulation
Published in
Frontiers in Neuroscience, February 2016
DOI 10.3389/fnins.2016.00030
Pubmed ID
Authors

Katharine A. Dunlop, Blake Woodside, Jonathan Downar

Abstract

The term "eating disorders" (ED) encompasses a wide variety of disordered eating and compensatory behaviors, and so the term is associated with considerable clinical and phenotypic heterogeneity. This heterogeneity makes optimizing treatment techniques difficult. One class of treatments is non-invasive brain stimulation (NIBS). NIBS, including repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), are accessible forms of neuromodulation that alter the cortical excitability of a target brain region. It is crucial for NIBS to be successful that the target is well selected for the patient population in question. Targets may best be selected by stepping back from conventional DSM-5 diagnostic criteria to identify neural substrates of more basic phenotypes, including behavior related to rewards and punishment, cognitive control, and social processes. These phenotypic dimensions have been recently laid out by the Research Domain Criteria (RDoC) initiative. Consequently, this review is intended to identify potential dimensions as outlined by the RDoC and the underlying behavioral and neurobiological targets associated with ED. This review will also identify candidate targets for NIBS based on these dimensions and review the available literature on rTMS and tDCS in ED. This review systematically reviews abnormal neural circuitry in ED within the RDoC framework, and also systematically reviews the available literature investigating NIBS as a treatment for ED.

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X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
Canada 1 <1%
Unknown 133 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 24 18%
Student > Ph. D. Student 21 16%
Student > Doctoral Student 12 9%
Student > Master 10 7%
Student > Bachelor 8 6%
Other 18 13%
Unknown 42 31%
Readers by discipline Count As %
Psychology 37 27%
Neuroscience 21 16%
Medicine and Dentistry 10 7%
Agricultural and Biological Sciences 2 1%
Engineering 2 1%
Other 8 6%
Unknown 55 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 February 2016.
All research outputs
#14,535,626
of 25,371,288 outputs
Outputs from Frontiers in Neuroscience
#5,782
of 11,538 outputs
Outputs of similar age
#144,714
of 311,612 outputs
Outputs of similar age from Frontiers in Neuroscience
#82
of 176 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,538 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,612 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 176 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.