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Estimation of Bounded and Unbounded Trajectories in Diffusion MRI

Overview of attention for article published in Frontiers in Neuroscience, March 2016
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Title
Estimation of Bounded and Unbounded Trajectories in Diffusion MRI
Published in
Frontiers in Neuroscience, March 2016
DOI 10.3389/fnins.2016.00129
Pubmed ID
Authors

Lipeng Ning, Carl-Fredrik Westin, Yogesh Rathi

Abstract

Disentangling the tissue microstructural information from the diffusion magnetic resonance imaging (dMRI) measurements is quite important for extracting brain tissue specific measures. The autocorrelation function of diffusing spins is key for understanding the relation between dMRI signals and the acquisition gradient sequences. In this paper, we demonstrate that the autocorrelation of diffusion in restricted or bounded spaces can be well approximated by exponential functions. To this end, we propose to use the multivariate Ornstein-Uhlenbeck (OU) process to model the matrix-valued exponential autocorrelation function of three-dimensional diffusion processes with bounded trajectories. We present detailed analysis on the relation between the model parameters and the time-dependent apparent axon radius and provide a general model for dMRI signals from the frequency domain perspective. For our experimental setup, we model the diffusion signal as a mixture of two compartments that correspond to diffusing spins with bounded and unbounded trajectories, and analyze the corpus-callosum in an ex-vivo data set of a monkey brain.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 6%
Unknown 16 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 29%
Student > Doctoral Student 3 18%
Student > Ph. D. Student 3 18%
Student > Bachelor 1 6%
Professor 1 6%
Other 4 24%
Readers by discipline Count As %
Medicine and Dentistry 4 24%
Physics and Astronomy 4 24%
Engineering 2 12%
Business, Management and Accounting 1 6%
Unspecified 1 6%
Other 3 18%
Unknown 2 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 March 2016.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from Frontiers in Neuroscience
#10,137
of 11,541 outputs
Outputs of similar age
#272,335
of 315,347 outputs
Outputs of similar age from Frontiers in Neuroscience
#154
of 177 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
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