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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Eye As a Biomarker for Alzheimer's Disease
|
|---|---|
| Published in |
Frontiers in Neuroscience, November 2016
|
| DOI | 10.3389/fnins.2016.00536 |
| Pubmed ID | |
| Authors |
Jeremiah K. H. Lim, Qiao-Xin Li, Zheng He, Algis J. Vingrys, Vickie H. Y. Wong, Nicolas Currier, Jamie Mullen, Bang V. Bui, Christine T. O. Nguyen |
| Abstract |
Alzheimer's disease (AD) is a progressive neurodegenerative disorder resulting in dementia and eventual death. It is the leading cause of dementia and the number of cases are projected to rise in the next few decades. Pathological hallmarks of AD include the presence of hyperphosphorylated tau and amyloid protein deposition. Currently, these pathological biomarkers are detected either through cerebrospinal fluid analysis, brain imaging or post-mortem. Though effective, these methods are not widely available due to issues such as the difficulty in acquiring samples, lack of infrastructure or high cost. Given that the eye possesses clear optics and shares many neural and vascular similarities to the brain, it offers a direct window to cerebral pathology. These unique characteristics lend itself to being a relatively inexpensive biomarker for AD which carries the potential for wide implementation. The development of ocular biomarkers can have far implications in the discovery of treatments which can improve the quality of lives of patients. In this review, we consider the current evidence for ocular biomarkers in AD and explore potential future avenues of research in this area. |
X Demographics
The data shown below were collected from the profiles of 37 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 14 | 38% |
| United Kingdom | 3 | 8% |
| Spain | 2 | 5% |
| Australia | 2 | 5% |
| Canada | 1 | 3% |
| Brazil | 1 | 3% |
| Japan | 1 | 3% |
| Kenya | 1 | 3% |
| Unknown | 12 | 32% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 28 | 76% |
| Scientists | 5 | 14% |
| Practitioners (doctors, other healthcare professionals) | 3 | 8% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 342 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | <1% |
| Switzerland | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 339 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 58 | 17% |
| Researcher | 50 | 15% |
| Student > Master | 34 | 10% |
| Student > Doctoral Student | 26 | 8% |
| Student > Bachelor | 26 | 8% |
| Other | 61 | 18% |
| Unknown | 87 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 57 | 17% |
| Neuroscience | 45 | 13% |
| Biochemistry, Genetics and Molecular Biology | 27 | 8% |
| Engineering | 25 | 7% |
| Agricultural and Biological Sciences | 20 | 6% |
| Other | 65 | 19% |
| Unknown | 103 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 32. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 November 2020.
All research outputs
#1,228,102
of 25,374,917 outputs
Outputs from Frontiers in Neuroscience
#538
of 11,541 outputs
Outputs of similar age
#24,623
of 417,813 outputs
Outputs of similar age from Frontiers in Neuroscience
#6
of 141 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,541 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 417,813 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 141 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.