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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Multiple Single-Unit Long-Term Tracking on Organotypic Hippocampal Slices Using High-Density Microelectrode Arrays
|
|---|---|
| Published in |
Frontiers in Neuroscience, November 2016
|
| DOI | 10.3389/fnins.2016.00537 |
| Pubmed ID | |
| Authors |
Wei Gong, Jure Senčar, Douglas J. Bakkum, David Jäckel, Marie Engelene J. Obien, Milos Radivojevic, Andreas R. Hierlemann |
| Abstract |
A novel system to cultivate and record from organotypic brain slices directly on high-density microelectrode arrays (HD-MEA) was developed. This system allows for continuous recording of electrical activity of specific individual neurons at high spatial resolution while monitoring at the same time, neuronal network activity. For the first time, the electrical activity patterns of single neurons and the corresponding neuronal network in an organotypic hippocampal slice culture were studied during several consecutive weeks at daily intervals. An unsupervised iterative spike-sorting algorithm, based on PCA and k-means clustering, was developed to assign the activities to the single units. Spike-triggered average extracellular waveforms of an action potential recorded across neighboring electrodes, termed "footprints" of single-units were generated and tracked over weeks. The developed system offers the potential to study chronic impacts of drugs or genetic modifications on individual neurons in slice preparations over extended times. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 50% |
| Australia | 1 | 25% |
| Switzerland | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 105 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | <1% |
| United States | 1 | <1% |
| Germany | 1 | <1% |
| Unknown | 102 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 35 | 33% |
| Researcher | 19 | 18% |
| Student > Master | 8 | 8% |
| Student > Bachelor | 8 | 8% |
| Professor | 4 | 4% |
| Other | 11 | 10% |
| Unknown | 20 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 33 | 31% |
| Engineering | 20 | 19% |
| Agricultural and Biological Sciences | 8 | 8% |
| Biochemistry, Genetics and Molecular Biology | 5 | 5% |
| Medicine and Dentistry | 4 | 4% |
| Other | 14 | 13% |
| Unknown | 21 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 December 2016.
All research outputs
#15,755,393
of 25,394,764 outputs
Outputs from Frontiers in Neuroscience
#6,696
of 11,544 outputs
Outputs of similar age
#230,990
of 415,604 outputs
Outputs of similar age from Frontiers in Neuroscience
#66
of 138 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,544 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 415,604 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 138 others from the same source and published within six weeks on either side of this one. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.