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Development and Function of the Blood-Brain Barrier in the Context of Metabolic Control

Overview of attention for article published in Frontiers in Neuroscience, April 2017
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Title
Development and Function of the Blood-Brain Barrier in the Context of Metabolic Control
Published in
Frontiers in Neuroscience, April 2017
DOI 10.3389/fnins.2017.00224
Pubmed ID
Authors

Roberta Haddad-Tóvolli, Nathalia R. V. Dragano, Albina F. S. Ramalho, Licio A. Velloso

Abstract

Under physiological conditions, the brain consumes over 20% of the whole body energy supply. The blood-brain barrier (BBB) allows dynamic interactions between blood capillaries and the neuronal network in order to provide an adequate control of molecules that are transported in and out of the brain. Alterations in the BBB structure and function affecting brain accessibility to nutrients and exit of toxins are found in a number of diseases, which in turn may disturb brain function and nutrient signaling. In this review we explore the major advances obtained in the understanding of the BBB development and how its structure impacts on function. Furthermore, we focus on the particularities of the barrier permeability in the hypothalamus, its role in metabolic control and the potential impact of hypothalamic BBB abnormities in metabolic related diseases.

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The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 286 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 <1%
Unknown 285 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 49 17%
Student > Bachelor 43 15%
Student > Ph. D. Student 38 13%
Student > Master 28 10%
Student > Doctoral Student 15 5%
Other 28 10%
Unknown 85 30%
Readers by discipline Count As %
Neuroscience 57 20%
Biochemistry, Genetics and Molecular Biology 37 13%
Medicine and Dentistry 26 9%
Agricultural and Biological Sciences 25 9%
Engineering 10 3%
Other 39 14%
Unknown 92 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2023.
All research outputs
#15,173,117
of 25,382,440 outputs
Outputs from Frontiers in Neuroscience
#6,404
of 11,542 outputs
Outputs of similar age
#168,962
of 323,266 outputs
Outputs of similar age from Frontiers in Neuroscience
#119
of 208 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,542 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,266 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 208 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.