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Activation of Brain Somatostatin Signaling Suppresses CRF Receptor-Mediated Stress Response

Overview of attention for article published in Frontiers in Neuroscience, April 2017
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Title
Activation of Brain Somatostatin Signaling Suppresses CRF Receptor-Mediated Stress Response
Published in
Frontiers in Neuroscience, April 2017
DOI 10.3389/fnins.2017.00231
Pubmed ID
Authors

Andreas Stengel, Yvette F. Taché

Abstract

Corticotropin-releasing factor (CRF) is the hallmark brain peptide triggering the response to stress and mediates-in addition to the stimulation of the hypothalamus-pituitary-adrenal (HPA) axis-other hormonal, behavioral, autonomic and visceral components. Earlier reports indicate that somatostatin-28 injected intracerebroventricularly counteracts the acute stress-induced ACTH and catecholamine release. Mounting evidence now supports that activation of brain somatostatin signaling exerts a broader anti-stress effect by blunting the endocrine, autonomic, behavioral (with a focus on food intake) and visceral gastrointestinal motor responses through the involvement of distinct somatostatin receptor subtypes.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 2%
Unknown 55 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 16%
Student > Bachelor 9 16%
Student > Doctoral Student 7 13%
Student > Postgraduate 6 11%
Researcher 5 9%
Other 11 20%
Unknown 9 16%
Readers by discipline Count As %
Neuroscience 16 29%
Agricultural and Biological Sciences 9 16%
Biochemistry, Genetics and Molecular Biology 6 11%
Medicine and Dentistry 4 7%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 6 11%
Unknown 13 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 May 2017.
All research outputs
#19,951,180
of 25,382,440 outputs
Outputs from Frontiers in Neuroscience
#8,671
of 11,542 outputs
Outputs of similar age
#233,558
of 323,623 outputs
Outputs of similar age from Frontiers in Neuroscience
#162
of 209 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,542 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,623 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 209 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.