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Emerging Signaling Pathway in Arcuate Feeding-Related Neurons: Role of the Acbd7

Overview of attention for article published in Frontiers in Neuroscience, June 2017
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Title
Emerging Signaling Pathway in Arcuate Feeding-Related Neurons: Role of the Acbd7
Published in
Frontiers in Neuroscience, June 2017
DOI 10.3389/fnins.2017.00328
Pubmed ID
Authors

Damien Lanfray, Denis Richard

Abstract

The understanding of the mechanisms whereby energy balance is regulated is essential to the unraveling of the pathophysiology of obesity. In the last three decades, focus was put on the metabolic role played by the hypothalamic neurons expressing proopiomelanocortin (POMC) and cocaine and amphetamine regulated transcript (CART) and the neurons co-localizing agouti-related peptide (AgRP), neuropeptide Y (NPY), and gamma-aminobutyric acid (GABA). These neurons are part of the leptin-melanocortin pathway, whose role is key in energy balance regulation. More recently, the metabolic involvement of further hypothalamic uncharacterized neuron populations has been suggested. In this review, we discuss the potential homeostatic implication of hypothalamic GABAergic neurons that produce Acyl-Coa-binding domain containing protein 7 (ACBD7), precursor of the nonadecaneuropeptide (NDN), which has recently been characterized as a potent anorexigenic neuropeptide capable of relaying the leptin anorectic/thermogenic effect via the melanocortin system.

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The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 22%
Student > Master 7 17%
Researcher 4 10%
Student > Bachelor 3 7%
Student > Doctoral Student 2 5%
Other 5 12%
Unknown 11 27%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 27%
Neuroscience 7 17%
Agricultural and Biological Sciences 4 10%
Psychology 2 5%
Medicine and Dentistry 2 5%
Other 2 5%
Unknown 13 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 July 2017.
All research outputs
#15,742,933
of 25,382,440 outputs
Outputs from Frontiers in Neuroscience
#6,691
of 11,542 outputs
Outputs of similar age
#181,283
of 329,377 outputs
Outputs of similar age from Frontiers in Neuroscience
#115
of 194 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,542 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,377 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 194 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.