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JAKE® Multimodal Data Capture System: Insights from an Observational Study of Autism Spectrum Disorder

Overview of attention for article published in Frontiers in Neuroscience, September 2017
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Title
JAKE® Multimodal Data Capture System: Insights from an Observational Study of Autism Spectrum Disorder
Published in
Frontiers in Neuroscience, September 2017
DOI 10.3389/fnins.2017.00517
Pubmed ID
Authors

Seth L. Ness, Nikolay V. Manyakov, Abigail Bangerter, David Lewin, Shyla Jagannatha, Matthew Boice, Andrew Skalkin, Geraldine Dawson, Yvette M. Janvier, Matthew S. Goodwin, Robert Hendren, Bennett Leventhal, Frederick Shic, Walter Cioccia, Gahan Pandina

Abstract

Objective: To test usability and optimize the Janssen Autism Knowledge Engine (JAKE®) system's components, biosensors, and procedures used for objective measurement of core and associated symptoms of autism spectrum disorder (ASD) in clinical trials. Methods: A prospective, observational study of 29 children and adolescents with ASD using the JAKE system was conducted at three sites in the United States. This study was designed to establish the feasibility of the JAKE system and to learn practical aspects of its implementation. In addition to information collected by web and mobile components, wearable biosensor data were collected both continuously in natural settings and periodically during a battery of experimental tasks administered in laboratory settings. This study is registered at clinicaltrials.gov, NCT02299700. Results: Feedback collected throughout the study allowed future refinements to be planned for all components of the system. The Autism Behavior Inventory (ABI), a parent-reported measure of ASD core and associated symptoms, performed well. Among biosensors studied, the eye-tracker, sleep monitor, and electrocardiogram were shown to capture high quality data, whereas wireless electroencephalography was difficult to use due to its form factor. On an exit survey, the majority of parents rated their overall reaction to JAKE as positive/very positive. No significant device-related events were reported in the study. Conclusion: The results of this study, with the described changes, demonstrate that the JAKE system is a viable, useful, and safe platform for use in clinical trials of ASD, justifying larger validation and deployment studies of the optimized system.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 144 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 144 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 30 21%
Student > Bachelor 14 10%
Student > Master 12 8%
Student > Doctoral Student 11 8%
Other 9 6%
Other 19 13%
Unknown 49 34%
Readers by discipline Count As %
Psychology 26 18%
Medicine and Dentistry 12 8%
Neuroscience 10 7%
Computer Science 8 6%
Social Sciences 8 6%
Other 29 20%
Unknown 51 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 October 2017.
All research outputs
#16,919,456
of 25,654,806 outputs
Outputs from Frontiers in Neuroscience
#7,577
of 11,659 outputs
Outputs of similar age
#199,643
of 329,381 outputs
Outputs of similar age from Frontiers in Neuroscience
#137
of 169 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,659 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,381 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 169 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.